Immune activation kickstarts the gut microbiota

The gut microbiota regulates intestinal immunity, but whether immune activation reciprocally alters gut commensals is unknown. In this issue of Cell Host & Microbe, Becattini et al. used a reductionist approach, incorporating gnotobiotic mouse models and multi-omics analyses, to address how gut...

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Bibliographic Details
Published in:Cell host & microbe 2021-03, Vol.29 (3), p.318-320
Main Author: Guo, Chun-Jun
Format: Article
Language:English
Subjects:
Animals
Gastrointestinal Microbiome
Germ-Free Life
Mice
Symbiosis
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Summary:The gut microbiota regulates intestinal immunity, but whether immune activation reciprocally alters gut commensals is unknown. In this issue of Cell Host & Microbe, Becattini et al. used a reductionist approach, incorporating gnotobiotic mouse models and multi-omics analyses, to address how gut commensals respond and adapt to acute immune activation. The gut microbiota regulates intestinal immunity, but whether immune activation reciprocally alters gut commensals is unknown. In this issue of Cell Host & Microbe, Becattini et al. used a reductionist approach, incorporating gnotobiotic mouse models and multi-omics analyses, to address how gut commensals respond and adapt to acute immune activation.
ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2021.02.012