The pattern of runs of homozygosity and genomic inbreeding in world-wide sheep populations

Genome-wide pattern of runs of homozygosity (ROH) across ovine genome can provide a useful resource for studying diversity and demography history in sheep. We analyzed 50 k SNPs chip data of 2536 animals to identify pattern, distribution and level of ROHs in 68 global sheep populations. A total of 6...

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Bibliographic Details
Published in:Genomics (San Diego, Calif.) Calif.), 2021-05, Vol.113 (3), p.1407-1415
Main Authors: Nosrati, Maryam, Asadollahpour Nanaei, Hojjat, Javanmard, Arash, Esmailizadeh, Ali
Format: Article
Language:English
Subjects:
Animals
Autozygosity
Cattle
Genome
Genomic inbreeding
Genomics
Genotype
Homozygote
Inbreeding
Polymorphism, Single Nucleotide
ROH hotspot
Runs of homozygosity
Sheep
Sheep - genetics
Swine
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Summary:Genome-wide pattern of runs of homozygosity (ROH) across ovine genome can provide a useful resource for studying diversity and demography history in sheep. We analyzed 50 k SNPs chip data of 2536 animals to identify pattern, distribution and level of ROHs in 68 global sheep populations. A total of 60,301 ROHs were detected in all breeds. The majority of the detected ROHs were
ISSN:0888-7543
1089-8646
DOI:10.1016/j.ygeno.2021.03.005