Extracellular buffer choice influences acid-base responses and gastrointestinal symptoms

To compare the bicarbonate kinetics and gastrointestinal (GI) symptom responses between an equal dose of sodium bicarbonate and sodium citrate using delayed-release capsules. Thirteen active males (age 20.5 ± 2.1 y, height 1.8 ± 0.1 m and body mass [BM] 76.5 ± 9.6 kg) consumed either 0.3 g . kg −1 B...

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Bibliographic Details
Published in:Research in sports medicine 2021-11, Vol.29 (6), p.505-516
Main Authors: Peacock, J., Sparks, S.A., Middlebrook, I., Hilton, N.P., Tinnion, D., Leach, N., Saunders, B., McNaughton, L.R.
Format: Article
Language:English
Subjects:
Alkalosis
delayed-release capsules
Sodium
sodium bicarbonate
sodium citrate
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Summary:To compare the bicarbonate kinetics and gastrointestinal (GI) symptom responses between an equal dose of sodium bicarbonate and sodium citrate using delayed-release capsules. Thirteen active males (age 20.5 ± 2.1 y, height 1.8 ± 0.1 m and body mass [BM] 76.5 ± 9.6 kg) consumed either 0.3 g . kg −1 BM sodium bicarbonate, sodium citrate or a placebo, using a double-blind, randomized crossover design. Blood bicarbonate ion (HCO 3 − ) concentration, pH and GI symptoms were measured pre-consumption and every 10 min for 180 min post-consumption. Blood HCO 3 − concentration (P
ISSN:1543-8627
1543-8635
DOI:10.1080/15438627.2021.1896517