Pivotal Role of Heart for Orthostasis: Left Ventricular Untwisting Mechanics and Physical Fitness

Augmentation of left ventricular (LV) untwisting due to central hypovolemia is likely to be a compensatory mechanism for maintaining stroke volume, which is reduced by a decrease in cardiac filling during orthostatic stress. Orthostatic intolerance observed in both high and low fitness levels may be...

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Bibliographic Details
Published in:Exercise and sport sciences reviews 2021-04, Vol.49 (2), p.88-98
Main Authors: Shibata, Shigeki, Hirabuki, Kazukuni, Hata, Noritaka, Suzuki, Rina, Suda, Tomoya, Uechi, Takahiro, Hirasawa, Ai
Format: Article
Language:English
Subjects:
Dizziness
Exercise
Heart
Humans
Physical Fitness
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Summary:Augmentation of left ventricular (LV) untwisting due to central hypovolemia is likely to be a compensatory mechanism for maintaining stroke volume, which is reduced by a decrease in cardiac filling during orthostatic stress. Orthostatic intolerance observed in both high and low fitness levels may be explained by the impaired response of LV untwisting due to central hypovolemia.
ISSN:0091-6331
1538-3008
DOI:10.1249/JES.0000000000000247