Bioimpedance Spectroscopy: Basics and Applications

In this review, we aim to introduce the reader to the technique of electrical impedance spectroscopy (EIS) with a focus on its biological, biomaterials, and medical applications. We explain the theoretical and experimental aspects of the EIS with the details essential for biological studies, i.e., i...

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Bibliographic Details
Published in:ACS biomaterials science & engineering 2021-06, Vol.7 (6), p.1962-1986
Main Authors: Stupin, Daniil D, Kuzina, Ekaterina A, Abelit, Anna A, Emelyanov, Anton K, Nikolaev, Dmitrii M, Ryazantsev, Mikhail N, Koniakhin, Sergei V, Dubina, Michael V
Format: Article
Language:English
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Summary:In this review, we aim to introduce the reader to the technique of electrical impedance spectroscopy (EIS) with a focus on its biological, biomaterials, and medical applications. We explain the theoretical and experimental aspects of the EIS with the details essential for biological studies, i.e., interaction of metal electrodes with biological matter and liquids, strategies of measurement rate increasing, noise reduction in bio-EIS experiments, etc. We also give various examples of successful bio-EIS practical implementations in science and technology, from whole-body health monitoring and sensors for vision prosthetic care to single living cell examination platforms, virus disease research, biomolecules detection, and implementation of novel biomaterials. The present review can be used as a bio-EIS tutorial for students as well as a handbook for scientists and engineers because of the extensive references covering the contemporary research papers in the field.
ISSN:2373-9878
2373-9878
DOI:10.1021/acsbiomaterials.0c01570