Relationship between body mass index and malignancy rates of MRI-guided breast biopsies: impact of clinicodemographic factors

Purpose To determine the positive predictive value (PPV) of magnetic resonance imaging (MRI)-guided breast biopsy stratified by body mass index (BMI). Secondary endpoints include evaluation of indications for breast MRI and identification of factors associated with malignant biopsy. Methods We retro...

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Bibliographic Details
Published in:Breast cancer research and treatment 2021-08, Vol.188 (3), p.739-747
Main Authors: Tang, Annie, Cohan, Caitlin M., Hansen, Keith S., Beattie, Genna, Greenwood, Heather I., Mukhtar, Rita A.
Format: Article
Language:English
Subjects:
Biopsy
Body mass index
Breast
Breast cancer
Cancer research
Comparative analysis
Epidemiology
Magnetic resonance imaging
Malignancy
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Oncology
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Summary:Purpose To determine the positive predictive value (PPV) of magnetic resonance imaging (MRI)-guided breast biopsy stratified by body mass index (BMI). Secondary endpoints include evaluation of indications for breast MRI and identification of factors associated with malignant biopsy. Methods We retrospectively analyzed results of MRI-guided breast biopsies in a consecutive cohort of women at a single institution between 2014 and 2019. The PPV was compared between BMI subgroups and the overall group by the one-sample z -test. Factors associated with malignant biopsy were analyzed using multivariate regression analysis. Results Among 427 MRI-guided breast biopsies, the PPV was significantly higher in patients with a BMI ≥ 35 compared to BMI 
ISSN:0167-6806
1573-7217
DOI:10.1007/s10549-021-06189-5