Essential Oils of Polyalthia suberosa Leaf and Twig and Their Cytotoxic and Antimicrobial Activities

Essential oils from the leaf and twig of Polyalthia suberosa (Roxb.) Thwaites were analyzed using GC/MS/FID. A total of sixty‐three constituents were namely identified accounting for 96.03 and 94.12 % in the hydrodistilled oils of the leaf and twig, respectively. Monoterpenes, monoterpenoids, sesqui...

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Bibliographic Details
Published in:Chemistry & biodiversity 2021-05, Vol.18 (5), p.e2100020-n/a
Main Authors: The, Son Ninh, Le Tuan, Anh, Thu, Thuy Dinh Thi, Dinh, Luyen Nguyen, Thi, Tuyen Tran
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
antimicrobial activity
Antimicrobial agents
Bicyclogermacrene
Camphene
Caryophyllene
Caryophyllene oxide
Coliforms
Constituents
Cytotoxicity
E coli
Essential oils
Humulene
Leaves
Minimum inhibitory concentration
Monoterpenes
Monoterpenoids
Oils & fats
Pinene
Polyalthia suberosa
Pseudomonas aeruginosa
Sesquiterpenes
Sesquiterpenoids
Tumor cell lines
Yeasts
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Summary:Essential oils from the leaf and twig of Polyalthia suberosa (Roxb.) Thwaites were analyzed using GC/MS/FID. A total of sixty‐three constituents were namely identified accounting for 96.03 and 94.12 % in the hydrodistilled oils of the leaf and twig, respectively. Monoterpenes, monoterpenoids, sesquiterpenes, and sesquiterpenoids were characteristic derivatives of P. suberosa essential oils. Sesquiterpenes bicyclogermacrene (26.26 %) and (E)‐caryophyllene (7.79 %), and monoterpene β‐pinene (12.71 %) were the major constituents of the leaf oil. Sesquiterpenes (E)‐caryophyllene (17.17 %) and α‐humulene (9.55 %), sesquiterpenoid caryophyllene oxide (9.41 %), and monoterpenes camphene (8.16 %) and tricyclene (6.35 %) were to be main components in the twig oil. The leaf oil indicated cytotoxic activity against three cancer cell lines HepG2, MCF7 and A549 with the IC50 values of 60.96–69.93 μg/mL, while the twig oil inhibited MCF7 with the IC50 value of 66.70 μg/mL. Additionally, the twig oil successfully suppressed the growth of the negative Gram bacterium Pseudomonas aeruginosa, fungus Aspergillus niger, and yeast Candida albicans with the same MIC value of 50 μg/mL, whereas the leaf oil had the same result on the negative Gram bacterium Escherichia coli.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202100020