The role of CE-MRA of the supraortic vessels in the detection of associated intracranial pathology

• Published in: Neurological sciences 2021-12, Vol.42 (12), p.5131-5137
• Main Authors: Calloni, Sonia Francesca, Perrotta, Marianna, Roveri, Luisa, Panni, Pietro, del Poggio, Anna, Vezzulli, Paolo Quintiliano, Filippi, Massimo, Falini, Andrea, Anzalone, Nicoletta
• Format: Article
• Language: English
• Subjects: Aneurysm; Aneurysms; Angiography; Disease; Dissection; Hematoma; Medicine; Medicine & Public Health; Neurology; Neuroradiology; Neurosciences; Neurosurgery; Occlusion; Original Article; Pathology; Psychiatry; Stenosis
• ISSN: 1590-1874; 1590-3478
• DOI: 10.1007/s10072-021-05222-1

Background Contrast-enhanced magnetic resonance angiography (CE-MRA) has become a very popular imaging technique in the evaluation of the extracranial vessels pathology, while it is not commonly used to rule out intracranial vascular pathology. On the contrary, 3D time of flight MRA (TOF-MRA) has a solid role in the study of intracranial arterial vessels disease. Materials and methods One hundred and eight patients were consecutively included in the study. All patients were submitted to a 3 Tesla 3D CE-MRA imaging to rule out extracranial vessels pathology. A comparison was made with a 3D-TOF sequence acquired at the same time in the assessment of intracranial vessels diseases such as steno-occlusion, dissection, and aneurysms. Results With regard to steno-occlusive disease, Spearman’s rank correlation coefficient was of 0.56 for stenosis detection and of 0.57 for occlusive disease detection. The two techniques shared similar results in the evaluation of anterior circulation, while 3D-TOF found higher grades of stenosis for posterior circulation. With regard to dissection, Spearman’s rank correlation coefficient was of 0.7. 3D-TOF depicted more intramural hematoma (Spearman’s rank = 0.46), while CE-MRA showed more pseudo-aneurysms (Spearman’s rank = 0.56). Both the technique equally evaluated the presence of intracranial aneurysms (Spearman’s rank = 1). Conclusion CE-MRA can be considered a reliable tool to rule out intracranial pathology associated to supraortic steno-occlusive disease, also allowing time reduction. In the suspicion of dissection a T1-weighted sequence has to be added to detect the presence of a subacute vessel wall hematoma.