Incidence and short-term outcomes of Kawasaki disease

Objective Kawasaki disease (KD) is a childhood vasculitis with conflicting reported North American trends in incidence and patient characteristics. Objectives: (1) determine KD incidence between 1995 and 2017; (2) compare patient characteristics by era and age group; (3) determine complication and c...

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Bibliographic Details
Published in:Pediatric research 2021-09, Vol.90 (3), p.670-677
Main Authors: Robinson, Cal, Chanchlani, Rahul, Gayowsky, Anastasia, Brar, Sandeep, Darling, Elizabeth, Demers, Catherine, Klowak, Jennifer, Knight, Braden, Kuenzig, Ellen, Mondal, Tapas, Parekh, Rulan, Seow, Hsien, Jimenez-Rivera, Carolina, Webster, Richard, Fung, Stephen, Benchimol, Eric I., Batthish, Michelle
Format: Article
Language:English
Subjects:
Adolescent
Age groups
Aneurysms
Child
Child, Preschool
Confidence intervals
Coronary vessels
Female
Humans
Incidence
Kawasaki disease
Male
Medicine
Medicine & Public Health
Mucocutaneous Lymph Node Syndrome - epidemiology
Mucocutaneous Lymph Node Syndrome - therapy
Ontario - epidemiology
Pediatric Surgery
Pediatrics
Population Study Article
Retrospective Studies
Risk Factors
Treatment Outcome
Trends
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Summary:Objective Kawasaki disease (KD) is a childhood vasculitis with conflicting reported North American trends in incidence and patient characteristics. Objectives: (1) determine KD incidence between 1995 and 2017; (2) compare patient characteristics by era and age group; (3) determine complication and cardiovascular follow-up rates. Methods We used population-based health administrative data to identify children (0–18 yr) hospitalized with KD in Ontario, Canada between 1995 and 2017. We excluded children with prior KD diagnosis or incomplete records. We determined the annualized incidence and follow-up trends. Results KD was diagnosed in 4,346 children between 1995 and 2017. Annual KD incidence was 22.0 (
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-021-01496-5