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To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial
Burn injuries can be associated with the incidence of disability and death, yet their management remains a costly difficult problem. We conducted this clinical trial to evaluate the period of wound healing with sea buckthorn dressings for the second‐degree burns and compare the results with 1% silve...
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Published in: | Wound repair and regeneration 2021-09, Vol.29 (5), p.732-740 |
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container_title | Wound repair and regeneration |
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creator | Abdullahzadeh, Mehrdad Shafiee, Saeed |
description | Burn injuries can be associated with the incidence of disability and death, yet their management remains a costly difficult problem. We conducted this clinical trial to evaluate the period of wound healing with sea buckthorn dressings for the second‐degree burns and compare the results with 1% silver sulfadiazine (SSD) dressings. This randomized triple‐blind clinical trial was conducted in a hospital in Isfahan, Iran. Fifty‐five patients suffering second‐degree burns were recruited through convenient sampling and randomly divided into two groups and treated with either sea buckthorn cream or 1% SSD. Wound dressings were done until complete wound healing was attained. The process of healing burns was monitored using the Bates‐Jensen Wound Assessment Tool; complete healing was determined by using the standard burn healing checklist. It was deduced that the period of healing second‐degree burns in the group treated with sea buckthorn cream was shorter than the group treated with 1% SSD (p |
doi_str_mv | 10.1111/wrr.12916 |
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We conducted this clinical trial to evaluate the period of wound healing with sea buckthorn dressings for the second‐degree burns and compare the results with 1% silver sulfadiazine (SSD) dressings. This randomized triple‐blind clinical trial was conducted in a hospital in Isfahan, Iran. Fifty‐five patients suffering second‐degree burns were recruited through convenient sampling and randomly divided into two groups and treated with either sea buckthorn cream or 1% SSD. Wound dressings were done until complete wound healing was attained. The process of healing burns was monitored using the Bates‐Jensen Wound Assessment Tool; complete healing was determined by using the standard burn healing checklist. It was deduced that the period of healing second‐degree burns in the group treated with sea buckthorn cream was shorter than the group treated with 1% SSD (p < 0.001). The results demonstrated the greater clinical efficacy of sea buckthorn cream over 1% SSD for healing second‐degree burns. It was concluded that using sea buckthorn dressing by reducing the period of wound healing can shorten the course of treatment of second‐degree burns as well as reduce the burden of care in health care services.</description><identifier>ISSN: 1067-1927</identifier><identifier>EISSN: 1524-475X</identifier><identifier>DOI: 10.1111/wrr.12916</identifier><identifier>PMID: 33792111</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Anti-Infective Agents, Local ; Bandages ; burns ; Burns - drug therapy ; dressings ; Hippophae ; Humans ; sea buckthorn ; silver sulfadiazine ; Silver Sulfadiazine - therapeutic use ; Sulfadiazine ; Wound Healing</subject><ispartof>Wound repair and regeneration, 2021-09, Vol.29 (5), p.732-740</ispartof><rights>2021 The Wound Healing Society.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3256-203fa956f21765a04f6e099f6dd75776a0e67dfd9bb0cfae3155b21ac4e830863</citedby><cites>FETCH-LOGICAL-c3256-203fa956f21765a04f6e099f6dd75776a0e67dfd9bb0cfae3155b21ac4e830863</cites><orcidid>0000-0003-3619-038X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33792111$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abdullahzadeh, Mehrdad</creatorcontrib><creatorcontrib>Shafiee, Saeed</creatorcontrib><title>To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial</title><title>Wound repair and regeneration</title><addtitle>Wound Repair Regen</addtitle><description>Burn injuries can be associated with the incidence of disability and death, yet their management remains a costly difficult problem. We conducted this clinical trial to evaluate the period of wound healing with sea buckthorn dressings for the second‐degree burns and compare the results with 1% silver sulfadiazine (SSD) dressings. This randomized triple‐blind clinical trial was conducted in a hospital in Isfahan, Iran. Fifty‐five patients suffering second‐degree burns were recruited through convenient sampling and randomly divided into two groups and treated with either sea buckthorn cream or 1% SSD. Wound dressings were done until complete wound healing was attained. The process of healing burns was monitored using the Bates‐Jensen Wound Assessment Tool; complete healing was determined by using the standard burn healing checklist. It was deduced that the period of healing second‐degree burns in the group treated with sea buckthorn cream was shorter than the group treated with 1% SSD (p < 0.001). The results demonstrated the greater clinical efficacy of sea buckthorn cream over 1% SSD for healing second‐degree burns. It was concluded that using sea buckthorn dressing by reducing the period of wound healing can shorten the course of treatment of second‐degree burns as well as reduce the burden of care in health care services.</description><subject>Anti-Infective Agents, Local</subject><subject>Bandages</subject><subject>burns</subject><subject>Burns - drug therapy</subject><subject>dressings</subject><subject>Hippophae</subject><subject>Humans</subject><subject>sea buckthorn</subject><subject>silver sulfadiazine</subject><subject>Silver Sulfadiazine - therapeutic use</subject><subject>Sulfadiazine</subject><subject>Wound Healing</subject><issn>1067-1927</issn><issn>1524-475X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kc9uFSEUh4nR2D-66AsYlnYxLTAXuLhrGltNmpg0NbqbMHDopTIwwow37aqP0Jfxhfok5XqrO1nACec731n8EDqg5IjWc7zO-YgyRcULtEs5WzQLyb-_rDURsqGKyR20V8oNIYRztXyNdtpWKlYnd9Hvq4RNGkadAU8rwOAcmAknhwto3M_mx7RKOWIdLS4-_IKMyxyctl7f-QjYZijFx2ucIh4h-2Q3s-s0V34FOmxavrb05CFOBa_9tKpqk6J9vH-wcJ0B6pocywd8gnNdkwZ_BxZP2Y8BKtNXh8Wm3t7osPnX4Q165XQo8Pb53Udfzz5enX5qLr6cfz49uWhMy7hoGGmdVlw4RqXgmiycAKKUE9ZKLqXQBIS0zqq-J8ZpaCnnPaPaLGDZkqVo99H7rXfM6ecMZeoGXwyEoCOkuXSMEynbOqYqerhFTU6lZHDdmP2g821HSbdJqaspdX9Squy7Z-3cD2D_kX9jqcDxFlj7ALf_N3XfLi-3yif_m6Ik</recordid><startdate>202109</startdate><enddate>202109</enddate><creator>Abdullahzadeh, Mehrdad</creator><creator>Shafiee, Saeed</creator><general>John Wiley & Sons, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3619-038X</orcidid></search><sort><creationdate>202109</creationdate><title>To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial</title><author>Abdullahzadeh, Mehrdad ; Shafiee, Saeed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3256-203fa956f21765a04f6e099f6dd75776a0e67dfd9bb0cfae3155b21ac4e830863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anti-Infective Agents, Local</topic><topic>Bandages</topic><topic>burns</topic><topic>Burns - drug therapy</topic><topic>dressings</topic><topic>Hippophae</topic><topic>Humans</topic><topic>sea buckthorn</topic><topic>silver sulfadiazine</topic><topic>Silver Sulfadiazine - therapeutic use</topic><topic>Sulfadiazine</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abdullahzadeh, Mehrdad</creatorcontrib><creatorcontrib>Shafiee, Saeed</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Wound repair and regeneration</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abdullahzadeh, Mehrdad</au><au>Shafiee, Saeed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial</atitle><jtitle>Wound repair and regeneration</jtitle><addtitle>Wound Repair Regen</addtitle><date>2021-09</date><risdate>2021</risdate><volume>29</volume><issue>5</issue><spage>732</spage><epage>740</epage><pages>732-740</pages><issn>1067-1927</issn><eissn>1524-475X</eissn><abstract>Burn injuries can be associated with the incidence of disability and death, yet their management remains a costly difficult problem. We conducted this clinical trial to evaluate the period of wound healing with sea buckthorn dressings for the second‐degree burns and compare the results with 1% silver sulfadiazine (SSD) dressings. This randomized triple‐blind clinical trial was conducted in a hospital in Isfahan, Iran. Fifty‐five patients suffering second‐degree burns were recruited through convenient sampling and randomly divided into two groups and treated with either sea buckthorn cream or 1% SSD. Wound dressings were done until complete wound healing was attained. The process of healing burns was monitored using the Bates‐Jensen Wound Assessment Tool; complete healing was determined by using the standard burn healing checklist. It was deduced that the period of healing second‐degree burns in the group treated with sea buckthorn cream was shorter than the group treated with 1% SSD (p < 0.001). The results demonstrated the greater clinical efficacy of sea buckthorn cream over 1% SSD for healing second‐degree burns. It was concluded that using sea buckthorn dressing by reducing the period of wound healing can shorten the course of treatment of second‐degree burns as well as reduce the burden of care in health care services.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>33792111</pmid><doi>10.1111/wrr.12916</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-3619-038X</orcidid></addata></record> |
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subjects | Anti-Infective Agents, Local Bandages burns Burns - drug therapy dressings Hippophae Humans sea buckthorn silver sulfadiazine Silver Sulfadiazine - therapeutic use Sulfadiazine Wound Healing |
title | To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial |
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