SARS-CoV-2 Not Detectable in Ocular Specimens of a Patient with a Past Infection

Purpose: To present a a case study that aims to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ocular tissue samples of a patient previously infected with COVID-19 and determine its transmissibility. Study Design: Case Report Results: In this case stu...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2021-05, Vol.29 (4), p.681-683
Main Authors: Felfeli, Tina, Mazzulli, Tony, Clark, Shawn T., El-Defrawy, Sherif R., Chan, Clara C.
Format: Article
Language:English
Subjects:
Coronavirus
COVID-19
Globe Rupture
Transmission
Viral Shedding
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Summary:Purpose: To present a a case study that aims to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ocular tissue samples of a patient previously infected with COVID-19 and determine its transmissibility. Study Design: Case Report Results: In this case study, SARS-CoV-2 was not detected in the vitreous and uveal tissue samples by RT-PCR for detection of three gene targets in a patient with a past COVID-19 infection 15 days prior to presention with a globe rupture. Conclusions: Our findings suggest that patients with long-term existence of SARS-CoV-2 at low detectable levels may not have active intraocular viral shedding. This is of particular importance as ophthalmic surgical procedures may potentiate virus spread from patients infected with SARS-CoV-2.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2021.1894458