Efficacy and safety of 755 nm Q-switched Alexandrite Laser for Hori’s nevus: a retrospective analysis of 482 Chinese women

• Published in: Lasers in medical science 2022-02, Vol.37 (1), p.345-351
• Main Authors: Huang, Lining, Zhong, Yiping, Yan, Tingting, Liu, Zhenfeng, Yang, Bin, Man, Mao-Qiang
• Format: Article
• Language: English
• Subjects: Alexandrite; China; Dentistry; Edema; Erythema; Female; Fluence; Humans; Hyperpigmentation; Laser Therapy; Lasers; Lasers, Solid-State - adverse effects; Medicine; Medicine & Public Health; Nevus; Nevus of Ota - radiotherapy; Nevus of Ota - surgery; Optical Devices; Optics; Original Article; Patients; Photonics; Q switched lasers; Quantum Optics; Retrospective Studies; Safety; Skin Neoplasms - radiotherapy; Skin Neoplasms - surgery; Treatment Outcome
• ISSN: 0268-8921; 1435-604X
• DOI: 10.1007/s10103-021-03257-6

To evaluate the efficacy and safety of 755 nm Q-Switched alexandrite laser for Hori’s nevus in a large cohort of Chinese women. We retrospectively analyzed the efficacy and safety of 755 nm Q-Switched alexandrite laser for Hori’s nevus. Reduction in pigment was evaluated using a 4-score method. A total of 482 patients, aged 16 to 52 years, were included in this analysis. Patients were treated with 755 nm Q-Switched alexandrite laser at fluence levels of 5–8 J/cm 2 for 2–4 treatment sessions. Following the treatments, 53% of patients showed over 75% reductions in pigment while 50–75% reductions in pigment were observed in 28% of patients. The rest displayed less than 50% improvements. Efficacy was positively correlated with the number of treatment sessions ( p