Physical comorbidity in Older-Age Bipolar Disorder (OABD) compared to the general population - a 3-year longitudinal prospective cohort study

The aim of this study was to examine the accumulation of chronic physical diseases in Older-Age Bipolar Disorder (OABD) as well as in individuals from the general aging population over a 3-year period. This prospective longitudinal study compared 101 patients with OABD receiving outpatient care (DOB...

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Bibliographic Details
Published in:Journal of affective disorders 2021-06, Vol.288, p.83-91
Main Authors: Beunders, Alexandra J.M., Kok, Almar A.L., Kosmas, Panagiotis C., Beekman, Aartjan T.F., Sonnenberg, Caroline M., Schouws, Sigfried N.T.M., Kupka, Ralph W., Stek, Max L., Dols, Annemiek
Format: Article
Language:English
Subjects:
Aging
Bipolar Disorder
Chronic Illness
Comorbidity
Geriatric Psychiatry
NCDs
Noncommunicable diseases
Older-Age Bipolar Disorder
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Summary:The aim of this study was to examine the accumulation of chronic physical diseases in Older-Age Bipolar Disorder (OABD) as well as in individuals from the general aging population over a 3-year period. This prospective longitudinal study compared 101 patients with OABD receiving outpatient care (DOBi cohort) with 2545 individuals from the general aging population (LASA cohort). The presence of eight major chronic diseases was asked at baseline and 3-year follow-up. Total number of diseases was the main outcome measure. Self-rated health (SRH, scale 1-5) was examined as a secondary outcome. Multilevel linear modelling of change was performed to estimate and test the observed change in both samples. At baseline, the number of chronic diseases was lower (b= -0.47, p
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2021.03.057