Prevalence of hypophosphatasia in adult patients in rheumatology

Hypophosphatasia (HPP) is a genetic disorder caused by one or more mutations in the alkaline phosphatase (ALP) gene, responsible for encoding tissue-specific ALP and for the mineralization process. Identification of the prevalence of HPP in rheumatology patients. Medical records of all adult rheumat...

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Bibliographic Details
Published in:Zeitschrift für Rheumatologie 2022-08, Vol.81 (6), p.513-519
Main Authors: Karakostas, P, Dolscheid-Pommerich, R, Hass, M D, Weber, N, Brossart, P, Schäfer, V S
Format: Article
Language:ger
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Summary:Hypophosphatasia (HPP) is a genetic disorder caused by one or more mutations in the alkaline phosphatase (ALP) gene, responsible for encoding tissue-specific ALP and for the mineralization process. Identification of the prevalence of HPP in rheumatology patients. Medical records of all adult rheumatology patients with pathologically low total ALP levels (
ISSN:1435-1250
DOI:10.1007/s00393-021-00994-5