Disparities in the symptomatic presentation of Moyamoya disease in the United States: A nationwide all-payer analysis

• Published in: Journal of clinical neuroscience 2021-05, Vol.87, p.92-96
• Main Authors: Fuentes, Angelica M., Chiu, Ryan G., Mehta, Ankit I.
• Format: Article
• Language: English
• Subjects: Intracranial hemorrhage; Moyamoya disease; Racial disparities; Seizure; Stroke
• ISSN: 0967-5868; 1532-2653
• DOI: 10.1016/j.jocn.2021.02.019

•MMD is a cerebrovascular disease manifesting with ischemic or hemorrhagic symptoms.•This disease is mainly studied in Asian populations due to its high prevalence.•In the US, presentations of MMD are associated with patient age, gender, and race. Moyamoya disease is a chronic occlusive cerebrovascular disease that can present with either hemorrhagic or ischemic symptoms. The objective of this study was to evaluate whether the symptomatology of Moyamoya disease differs according to patient demographic groups. In this study, we used the Nationwide Inpatient Sample (NIS) to investigate differences in the presentation of Moyamoya disease by age group, gender, and ethnicity from 2012 to 2016. After propensity score matching was utilized to control for overall comorbidity, the matched cohorts for each symptomatology were compared using a Chi-square test with respect to the potential risk factors of interest (i.e. age, sex, ethnicity) in order to generate multivariate reported P-values. A total of 4,474 patients met inclusion criteria. Patients presenting with ischemic stroke were more likely to be 65 years and older (p