Vitamin D, Bone Mineral Density and Serum IGF-1 Level in Non-ambulatory Children With Cerebral Palsy

Objective To compare serum 25-hydroxy vitamin D (25-OHD) status, bone mineral density and Insulin-like growth factor (IGF-1) level among children with cerebral palsy (CP) aged 1 to 8 years with age- and gender-matched controls. Methods A cross-sectional study enrolled 30 children in each group: CP w...

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Bibliographic Details
Published in:Indian pediatrics 2021-09, Vol.58 (9), p.836-838
Main Authors: Gwasikoti, Namita, Bhalla, Kapil, Kaushik, Jaya Shankar, Ghalaut, Veena Singh, Kundu, Zile Singh
Format: Article
Language:English
Subjects:
Bone Density
Cerebral Palsy - epidemiology
Child
Cross-Sectional Studies
Humans
Insulin-Like Growth Factor I
Maternal and Child Health
Medicine
Medicine & Public Health
Pediatric Surgery
Pediatrics
Research Paper
Vitamin D
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Summary:Objective To compare serum 25-hydroxy vitamin D (25-OHD) status, bone mineral density and Insulin-like growth factor (IGF-1) level among children with cerebral palsy (CP) aged 1 to 8 years with age- and gender-matched controls. Methods A cross-sectional study enrolled 30 children in each group: CP with epilepsy, CP without epilepsy, and healthy controls. Bone mineral density (BMD), serum 25-OHD levels, and serum insulin like growth factor (IGF)-1 levels were measured. Results z-scores of BMD [−1.80 (1.03), −2.12 (0.85) vs −1.40 (0.90); P
ISSN:0019-6061
0974-7559
DOI:10.1007/s13312-021-2303-6