Pupillometry provides a psychophysiological index of arousal level and cognitive effort during the performance of a visual-auditory dual-task in individuals with a history of concussion

• Published in: Vision research (Oxford) 2021-07, Vol.184, p.43-51
• Main Authors: Tapper, Anthony, Gonzalez, David, Nouredanesh, Mina, Niechwiej-Szwedo, Ewa
• Format: Article
• Language: English
• Subjects: Arousal; Athletes; Brain Concussion; Cognition; Divided attention; Executive Function; Humans; Pupil; Pupil size; Task Performance and Analysis; Traumatic brain injury; Working memory
• ISSN: 0042-6989; 1878-5646
• DOI: 10.1016/j.visres.2021.03.011

Research shows that concussions cause long-term deficits in executive functions when tested using challenging tasks with high cognitive load. The neurophysiological mechanism(s) associated with executive dysfunction are not well understood. Pupillometry provides a non-invasive index of arousal and cognitive load; therefore, the current study investigated whether pupillometry could help explain the persistent deficits in dual-task performance in individuals with a history of concussion (n = 14) compared to controls (n = 13). Participants were tested using a computerized Corsi block task which increased in difficulty as a function of set size (i.e., number of blocks to be remembered) and task condition (i.e., performed alone and concurrently with an auditory task). Pupil size was measured during the initial fixation prior to the Corsi task to assess arousal level, and during the encoding phase to assess task evoked pupil response. Results showed that: 1) in contrast to the control group, pupil size was not modulated by task condition in the concussed group indicating that arousal level was similar in the single and dual task; 2) task evoked pupil dilation increased as a function of set size in the single task in both groups, 3) in contrast to the control group, those with a history of concussion had similar pupil size during the single and dual task conditions. One interpretation of these results is that individuals with a history of concussion exert greater effort when performing relatively easier tasks, and they reach capacity limits when the cognitive load is lower in comparison to non-concussed individuals. In conclusion, pupillometry may provide insight into persisting deficits in executive functions following concussion(s).