Impact of Moringa Oleifera leaves supplementation on quality of life of people living with HIV: A double-blind randomized controlled trial

Purpose Advances in antiretroviral therapy (ART) and increased interest on nutritional interventions have led to improvements in life expectancy of people living with HIV (PLHIV). These have led to greater emphasis on their quality of life (QoL). This study was aimed at exploring the effects of Mori...

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Bibliographic Details
Published in:Quality of life research 2021-09, Vol.30 (9), p.2563-2571
Main Authors: Gambo, Aisha, Moodley, Indres, Babashani, Musa, Babalola, Tesleem K.
Format: Article
Language:English
Subjects:
Antiretroviral drugs
Clinical trials
Double-blind studies
HIV
Human immunodeficiency virus
Medicine
Medicine & Public Health
PACTR
PACTR201811722056449
Public Health
Quality of life
Quality of Life Research
Sociology
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Summary:Purpose Advances in antiretroviral therapy (ART) and increased interest on nutritional interventions have led to improvements in life expectancy of people living with HIV (PLHIV). These have led to greater emphasis on their quality of life (QoL). This study was aimed at exploring the effects of Moringa oleifera leaves supplementation on QoL of HIV-positive adults in Nigeria. Method A double-blind randomized controlled trial was conducted to determine the six months’ impact of consuming Moringa oleifera leaves powder as a nutritional supplement on the different domains of QoL of PLHIV that are on ART. Two hundred consented patients were randomly allocated to either Moringa Oleifera group (MOG) or control group (COG). The WHOQOL-HIV-BREF was used to assess QoL at baseline and at six-month follow-up. Results One hundred and seventy seven patients completed the study. At six-month follow-up, a significant ( p  
ISSN:0962-9343
1573-2649
DOI:10.1007/s11136-021-02842-0