Factors affecting the biological response of Graphene

• Published in: Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2021-07, Vol.203, p.111767-111767, Article 111767
• Main Authors: Magne, Tais Monteiro, de Oliveira Vieira, Thamires, Costa, Bianca, Alencar, Luciana Magalhães Rebelo, Ricci-Junior, Eduardo, Hu, Rui, Qu, Junle, Zamora-Ledezma, Camilo, Alexis, Frank, Santos-Oliveira, Ralph
• Format: Article
• Language: English
• Subjects: 2D materials; Biomedical; Carbon nanomaterials; Graphene oxide; Nanoparticles
• ISSN: 0927-7765; 1873-4367
• DOI: 10.1016/j.colsurfb.2021.111767

[Display omitted] •Biological behavior of grapheme.•Effect of cells and tissues exposed to grapheme.•Clinical and environmental impact when exposed to grapheme. Nanotechnology has gained significant importance in different fields of medical, electronic, and environmental science. This technology is founded on the use of materials at the nanoscale scale (1–100 nanometers) for various purposes, particularly in the biomedical area, where its application is growing daily due to the need of materials with advanced properties. Over the past few years, there has been a growing use for graphene and its derivative composite materials. However, different physico-chemical properties influence its biological response; therefore, further studies to explain the interactions of these nanomaterials with biological systems are critical. This review presents the current advances in the applications of graphene in biomedicine with a focus on the physico-chemical characteristics of the graphene family and their influences on biological interactions.