Inter-observer and Inter-vendor Variability in Strain Measurements in Patients with Single Right Ventricular Anatomy

Myocardial strain offers new insights into ventricular performance, There are software packages from several different companies used to ascertain this, and little data is available in patients with single right ventricle (sRV) physiology. We aimed to compare the analysis of two strain software appl...

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Bibliographic Details
Published in:Pediatric cardiology 2021-08, Vol.42 (6), p.1341-1349
Main Authors: Thompson, Alex J., O’Leary, Patrick W., Miller, Angela, Martineau, Sara, Reece, Chelsea, Breuer, Amanda, Eidem, Benjamin W., Qureshi, M. Yasir
Format: Article
Language:English
Subjects:
Cardiac Surgery
Cardiology
Electrical equipment and supplies industry
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Original Article
Physiological aspects
Software
Vascular Surgery
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Summary:Myocardial strain offers new insights into ventricular performance, There are software packages from several different companies used to ascertain this, and little data is available in patients with single right ventricle (sRV) physiology. We aimed to compare the analysis of two strain software applications using a cohort of patients with sRV for both inter-vendor and inter-observer variability. Echocardiograms from 85 patients with sRV (122 separate studies) were prospectively evaluated. All had Glenn and/or Fontan palliation. Longitudinal 4-chamber (4LS), inflow/outflow (IO), circumferential, and radial strain were assessed using Velocity Vector Imaging (VVI, Seimens, Munich) and Automated Functional Imaging (AFI, General Electric, Boston) software. In a subset of 45 patients (61 separate studies), strain measurements were obtained by two sonographers so a paired “inter-observer” analysis could be performed. A moderate correlation between measurements made by the two systems was observed. Circumferential strain assessment had the highest R value (0.77) with all others having R values 
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-021-02617-x