Pathological and Immunohistochemical Characterization of Thyroid Neoplasms in Cats

There are few pathological and immunohistochemical descriptions of thyroid neoplasms in cats. We investigated neoplasms of the thyroid in 31 cats (average age 15.6 years) in Southern Brazil. Most (96.8%) of these cases were classified as follicular adenomas and were predominantly unilateral and mult...

Full description

Saved in:
Bibliographic Details
Published in:Journal of comparative pathology 2021-04, Vol.184, p.44-55
Main Authors: Argenta, Fernando F., de Mello, Lauren S., Slaviero, Mônica, Cony, Fernanda G., Bandinelli, Marcele B., Pavarini, Saulo P., Driemeier, David, Sonne, Luciana
Format: Article
Language:English
Subjects:
calcitonin-negative neuroendocrine tumour
cats
immunohistochemistry
thyroid adenoma
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are few pathological and immunohistochemical descriptions of thyroid neoplasms in cats. We investigated neoplasms of the thyroid in 31 cats (average age 15.6 years) in Southern Brazil. Most (96.8%) of these cases were classified as follicular adenomas and were predominantly unilateral and multinodular. Histologically, macrofollicular adenomas were the most common type observed. Carcinomas represented 3.2% of the investigated tumours. By immunohistochemical labelling, thyroglobulin was expressed more commonly than paired box gene 8 or thyroid transcription factor 1 in the follicular adenomas. One carcinoma was immunopositive for thyroglobulin, pancytokeratin, chromogranin A and synaptophysin, suggestive of a calcitonin-negative neuroendocrine carcinoma.
ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2021.01.013