Effects of sesame, canola and sesame‐canola oils on body weight and composition in adults with type 2 diabetes mellitus: a randomized, triple‐blind, cross‐over clinical trial

• Published in: Journal of the science of food and agriculture 2021-11, Vol.101 (14), p.6083-6092
• Main Authors: Raeisi‐Dehkordi, Hamidreza, Amiri, Mojgan, Moghtaderi, Fatemeh, Zimorovat, Alireza, Rahmanian, Masoud, Mozaffari‐Khosravi, Hassan, Salehi‐Abargouei, Amin
• Format: Article
• Language: English
• Subjects: Adipose tissue; Adults; body composition; Body fat; Body mass; Body mass index; Body size; Body weight; Canola; Canola oil; Carbon monoxide; Clinical trials; Composition; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diet; dietary oils; Females; Oils & fats; Sesame oil; Sesamum; type 2 diabetes mellitus; Vegetable oils
• ISSN: 0022-5142; 1097-0010
• DOI: 10.1002/jsfa.11265

BACKGROUND Recent investigations have proposed that sesame and canola oils might affect body fat distribution. The present study aimed to examine the effects of sesame, canola and sesame‐canola (a blend of sesame and canola oils) oils on body weight and composition in adults with type 2 diabetes mellitus in the context of a randomized, triple‐blind, three‐way, cross‐over clinical trial. RESULTS Eligible participants were randomized to replace their regular dietary oil with sesame oil (SO), canola oil (CO) and sesame‐canola oil (SCO) (with 40% SO and 60% CO). Treatment periods lasted 9 weeks and were separated by 4‐week wash‐out periods. Body weight and composition were measured at the beginning, in the middle and at the end of each intervention phase. In total, 93 participants completed the study. After adjustment for confounders, within‐period changes were observed following SO and CO intake for body weight (0.34 ± 0.16 kg and 0.33 ± 0.17 kg) and visceral fat (0.13 ± 0.06% and 0.13 ± 0.05%, P