Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore

Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties usefu...

Full description

Saved in:
Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2021-05, Vol.36 (3), p.160-173
Main Author: Saavedra, Juan M
Format: Article
Language:English
Subjects:
Angiotensin Receptor Antagonists - adverse effects
Angiotensin Receptor Antagonists - therapeutic use
Angiotensin-Converting Enzyme Inhibitors - adverse effects
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Animals
Anti-Inflammatory Agents - therapeutic use
Antihypertensive Agents - therapeutic use
Antiviral Agents - adverse effects
Antiviral Agents - therapeutic use
COVID-19 - drug therapy
COVID-19 - metabolism
COVID-19 - physiopathology
COVID-19 - virology
Fibrinolytic Agents - therapeutic use
Humans
Renin-Angiotensin System - drug effects
SARS-CoV-2 - drug effects
SARS-CoV-2 - pathogenicity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties useful to treat inflammatory, age-related, neurodegenerative, and metabolic disorders of many organs including brain and lung.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00036.2020