Palladium-catalyzed carbonylative cyclization of benzyl chlorides with anthranils for the synthesis of 3-arylquinolin-2(1)-ones

An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1 H )-ones has been established. Through a palladium-catalyzed aminocarbonylation of benzyl chlorides with anthranils, a variety of 3-arylquinoin-2(1 H )-one products were obtained in moderate to excellent yields with good fun...

Full description

Saved in:
Bibliographic Details
Published in:Organic & biomolecular chemistry 2021-04, Vol.19 (16), p.3584-3588
Main Authors: Liu, Jian-Li, Xu, Ren-Rui, Wang, Wei, Qi, Xinxin, Wu, Xiao-Feng
Format: Article
Language:English
Subjects:
Carbonyls
Chlorides
Functional groups
NMR
Nuclear magnetic resonance
Palladium
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1 H )-ones has been established. Through a palladium-catalyzed aminocarbonylation of benzyl chlorides with anthranils, a variety of 3-arylquinoin-2(1 H )-one products were obtained in moderate to excellent yields with good functional group tolerance. An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1 H )-ones has been established.
ISSN:1477-0520
1477-0539
DOI:10.1039/d1ob00298h