Determination of the Phytochemical Composition and Antioxidant Potential of Eugenia copacabanensis and Myrciaria tenella Leaves (Myrtaceae) Using a Saccharomyces cerevisiae Model

Eugenia copacabanensis and Myrciaria tenella are present in restingas of the Atlantic Forest, but little information is available about their chemical and biological potential. In this context, the hexane, dichloromethane, ethyl acetate and butanol fractions from the leaves of methanolic extract wer...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry & biodiversity 2021-06, Vol.18 (6), p.e2100054-n/a
Main Authors: Carvalho Martins, Víctor, França, Liliana Princisval, Silva Ferreira, Yasmim, Pires, Daniele Cabral, Souza Cardoso, Bárbara, Pessanha de Araújo Santiago, Manuela Cristina, Pacheco, Sidney, Costa Souza, Marcelo, Riger, Cristiano Jorge, Oliveira Godoy, Ronoel Luiz, Geraldo de Carvalho, Mario
Format: Article
Language:English
Subjects:
Acetic acid
antioxidant activity
Antioxidants
Butanol
dereplication
Dichloromethane
Ethyl acetate
Eugenia copacabanensis
Fungi
Glutathione
Hexanes
High-performance liquid chromatography
Leaves
Liquid chromatography
Myrciaria
Myrciaria tenella
Oxidative stress
Phenolic compounds
Phenols
Saccharomyces cerevisiae
Yeast
yeast model
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Eugenia copacabanensis and Myrciaria tenella are present in restingas of the Atlantic Forest, but little information is available about their chemical and biological potential. In this context, the hexane, dichloromethane, ethyl acetate and butanol fractions from the leaves of methanolic extract were analyzed by GC/MS and HPLC‐DAD and the antioxidant potential was determined by DPPH and ABTS assays and using a Saccharomyces cerevisiae model. Dereplication allowed the identification of 68 compounds, 42 and 41 of which, respectively, are first reported here for E. copacabanensis and M. tenella. In vivo results revealed that the ethyl acetate and butanol fractions showed expressive antioxidant protection in the BY4741 and Δgsh1 strains, with greater impact on glutathione‐deficient cells. With a high diversity of phenolic compounds, these polar fractions of E. copacabanensis and M. tenella leaves are potential protectors against intracellular oxidative stress.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202100054