Comparison of the lesion formation and safety in ex vivo porcine heart study: Using ThermoCool SmartTouch and ThermoCool SmartTouch‐SF catheters

• Published in: Journal of cardiovascular electrophysiology 2021-08, Vol.32 (8), p.2077-2089
• Main Authors: Guo, Min, Qu, Lijuan, Zhang, Nan, Yan, Rui, Xue, Zheng, Sun, Meng, Wang, Rui
• Format: Article
• Language: English
• Subjects: Ablation; catheter; Catheters; lesion formation; Lesions; Myocardium; porcine heart; radiofrequency ablation
• ISSN: 1045-3873; 1540-8167
• DOI: 10.1111/jce.15066

Background The study was performed to compare the efficacy and safety during radiofrequency ablation (RFA) using ThermoCool SmartTouch (ST) and ThermoCool SmartTouch‐SF (STSF) catheters in the porcine heart. Methods and Results RFA was performed on the porcine myocardium by using two irrigated ablation catheters. Three groups were divided based on the different contact forces (CFs): low contact force (LCF) (1–3 g), medium contact force (MCF) (5–10 g), and high contact force (HCF) (15–20 g). In each group, RFA was delivered at four power settings of 30, 40, 50, 60 W. At each power, RFA was applied to reach the target ablation index (AI) of 350, 450, and 500. Altogether, 360 RF lesions were created by using 72 ablation conditions. AI value was positively correlated with lesion size using ST and STSF catheters. At a fixed power, lesion dimensions significantly smaller in the LCF group, whereas did not differ between MCF and HCF groups. Furthermore, at a fixed CF, lesion dimensions increased with power set at 40 W compared with 30 W but decreased with high‐power RF energy (50 and 60 W). Although the average lesion surface diameter and the maximum diameter was increased using the STSF catheter, there were no significant differences in LV between the two catheters. The steam pop provoked more frequently using ST catheter and showed a negative correlation with CF and positive correlation with high‐power energy. Conclusion The STSF catheter is safer and equally effective in lesion formation compared with the ST catheter. LV was increased along with the early increase of CF and power, whereas a further increase of CF and power significantly reduces the lesion size.