Renal impairment and its impact on clinical outcomes in patients who are critically ill with COVID‐19: a multicentre observational study

Summary Renal impairment is common in patients who are critically ill with coronavirus disease‐19 (COVID‐19). We examined the association between acute and chronic kidney disease with clinical outcomes in 372 patients with coronavirus disease‐19 admitted to four regional intensive care units between...

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Bibliographic Details
Published in:Anaesthesia 2021-03, Vol.76 (3), p.320-326
Main Authors: Gasparini, M., Khan, S., Patel, J. M., Parekh, D., Bangash, M. N., Stϋmpfle, R., Shah, A., Baharlo, B., Soni, S., Brett, S., Broomhead, R., Patel, P., Waheed, U., Templeton, M., Chotalia, M., Alderman, J., Beesley, E.
Format: Article
Language:English
Subjects:
acute kidney disease
Acute Kidney Injury - mortality
Adult
Aged
Aged, 80 and over
Causality
chronic kidney disease
Cohort Studies
Comorbidity
COVID-19 - mortality
COVID‐19
Critical Illness
England - epidemiology
Female
Hospital Mortality
Humans
Male
Middle Aged
Retrospective Studies
Risk Assessment
SARS-CoV-2
Severity of Illness Index
Young Adult
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Summary:Summary Renal impairment is common in patients who are critically ill with coronavirus disease‐19 (COVID‐19). We examined the association between acute and chronic kidney disease with clinical outcomes in 372 patients with coronavirus disease‐19 admitted to four regional intensive care units between 10 March 2020 and 31 July 2020. A total of 216 (58%) patients presented with COVID‐19 and renal impairment. Acute kidney injury and/or chronic kidney disease was associated with greater in‐hospital mortality compared with patients with preserved renal function (107/216 patients (50%) (95%CI 44–57) vs. 32/156 (21%) (95%CI 15–28), respectively; p 
ISSN:0003-2409
1365-2044
DOI:10.1111/anae.15293