Effective Control of Brain Metastases Irrespective of Distance from Isocenter in Single-isocenter Multitarget Stereotactic Radiosurgery

Few previous studies have evaluated the effectiveness of single-isocenter multitarget (SIMT) stereotactic radiosurgery (SRS) in clinical practice. Gross tumor volumes of 113 metastases in 13 patients were measured by contrast-enhanced magnetic resonance imaging. Prescribed doses were set at 20-24 Gy...

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Bibliographic Details
Published in:Anticancer research 2021-05, Vol.41 (5), p.2575-2581
Main Authors: Aoki, Ken, Nagatani, Yukihiro, Noma, Kazuo, Tsugawa, Takuya, Kono, Naoaki, Kida, Yukako, Harada, Naoki, Tanoue, Yoshihide, Watanabe, Yoshiyuki
Format: Article
Language:English
Subjects:
Aged
Brain
Brain cancer
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
Brain Neoplasms - radiotherapy
Brain Neoplasms - secondary
Disease-Free Survival
Dose-Response Relationship, Radiation
Female
Humans
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - pathology
Lung Neoplasms - radiotherapy
Magnetic resonance imaging
Male
Metastases
Metastasis
Middle Aged
Neuroimaging
Radiology
Radiosurgery
Radiosurgery - adverse effects
Radiosurgery - methods
Shrinkage
Surgery
Tumors
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Summary:Few previous studies have evaluated the effectiveness of single-isocenter multitarget (SIMT) stereotactic radiosurgery (SRS) in clinical practice. Gross tumor volumes of 113 metastases in 13 patients were measured by contrast-enhanced magnetic resonance imaging. Prescribed doses were set at 20-24 Gy. Based on tumor reduction rates (TRRs) measured before and after SIMT SRS, tumor shrinkage effect was categorized into four grades; almost disappeared: TRR=1, decreased: 0.3≤TRR
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.15036