Effect of the local probiotics in the therapy of periodontitis A randomized prospective study

Objectives The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in t...

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Bibliographic Details
Published in:International journal of dental hygiene 2022-05, Vol.20 (2), p.401-407
Main Authors: Minić, Ivan, Pejčić, Ana, Bradić‐Vasić, Marija
Format: Article
Language:English
Subjects:
Chronic Periodontitis - therapy
Dental Scaling - methods
Gum disease
Humans
Immune response
Patients
periodontal indices
Periodontal Pocket
Periodontitis
Pilot Projects
Plaque index
Probiotics
Probiotics - therapeutic use
Prospective Studies
Root Planing - methods
Statistical analysis
therapy
Topical application
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Summary:Objectives The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP). Methods The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment. Results Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p 
ISSN:1601-5029
1601-5037
DOI:10.1111/idh.12509