Epidemiology of tongue squamous cell carcinoma: A retrospective cohort study

Objective To analyze the epidemiological profile and the specific survival of patients diagnosed with tongue squamous cell carcinoma at the National Cancer Institute (INCA). Materials and methods Hospital Cancer Registry System Data and Mortality Information from 2007 to 2009 were retrieved in a ret...

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Bibliographic Details
Published in:Oral diseases 2023-03, Vol.29 (2), p.402-410
Main Authors: Silva Souto, Ana Carolina, Vieira Heimlich, Fernanda, Lima de Oliveira, Leticia, Bergmann, Anke, Dias, Fernando Luiz, Spíndola Antunes, Héliton, Melo, Andreia Cristina, Thuler, Luiz Claudio Santos, Cohen Goldemberg, Daniel
Format: Article
Language:English
Subjects:
Cancer
Carcinoma, Squamous Cell - epidemiology
Carcinoma, Squamous Cell - surgery
Cell survival
Cohort analysis
Epidemiology
Female
Humans
Male
Mortality
Neoplasm Staging
Oral cancer
oral squamous cell carcinoma
Patients
Prognosis
Retrospective Studies
specific survival
Squamous cell carcinoma
Surgery
survival
Tongue
tongue cancer
Tongue Neoplasms - epidemiology
Tongue Neoplasms - surgery
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Summary:Objective To analyze the epidemiological profile and the specific survival of patients diagnosed with tongue squamous cell carcinoma at the National Cancer Institute (INCA). Materials and methods Hospital Cancer Registry System Data and Mortality Information from 2007 to 2009 were retrieved in a retrospective cohort study of patients diagnosed with tongue squamous cell carcinoma. Specific survival was estimated using the Kaplan–Meier method. The association between independent variables and the risk of death was explored in a Cox proportional hazards regression model. Results A total of 346 patients were eligible, mostly male (77.5%), smokers (87.6%), with alcohol consumption (80.9%), with low education (65.6%), advanced staging at the time of diagnosis (71.1%), and presenting a high mortality rate (72.5%). In total, 44.5% of patients underwent a surgical approach alone or associated with another treatment modality, of which 85.1% of patients underwent neck dissection and 90.1% had free surgical margins. Specific survival was 40.6% in two years and 31.2% in five years. Conclusion The 5‐year specific survival was considered worse in individuals over 60 years, and who did not undergo surgical treatment or had surgery associated with another treatment, compared to patients undergoing isolated surgery.
ISSN:1354-523X
1601-0825
DOI:10.1111/odi.13897