Efficacy of dance for Parkinson’s disease: a pooled analysis of 372 patients

• Published in: Journal of neurology 2022-03, Vol.269 (3), p.1195-1208
• Main Authors: Hasan, Sara Mohamed, Alshafie, Somia, Hasabo, Elfatih A., Saleh, Ma’moun, Elnaiem, Walaa, Qasem, Aya, Alzu’bi, Yazan O., Khaled, Asmaa, Zaazouee, Mohamed Sayed, Ragab, Khaled Mohamed, Nourelden, Anas Zakarya, Doheim, Mohamed Fahmy
• Format: Article
• Language: English
• Subjects: Balance; Clinical trials; Cognition; Cognitive ability; Dance; Dance Therapy; Drug therapy; Exercise; Humans; Medicine; Medicine & Public Health; Meta-analysis; Motor activity; Movement disorders; Neurodegenerative diseases; Neurology; Neuroradiology; Neurosciences; Parkinson Disease - complications; Parkinson Disease - therapy; Parkinson's disease; Patients; Randomized Controlled Trials as Topic; Review; Tremor
• ISSN: 0340-5354; 1432-1459
• DOI: 10.1007/s00415-021-10589-4

Background Parkinson’s disease (PD) is a neurodegenerative disorder that presents with motor and nonmotor symptoms such as bradykinesia, resting tremor, postural instability, and cognitive and neuropsychiatric manifestations. Dance therapy or complex motor activity, besides pharmacological treatment, may have benefits in PD patients. Objective To assess the effect of dance in patients with PD. Methods We searched for clinical trials in PubMed, Scopus, and Web of Science, and Cochrane till April 2020 using relevant keywords. Data were extracted and pooled as mean difference (MD) with 95% confidence interval (CI) by Review Manager 5.3. Results Fourteen randomized controlled trials with 372 patients were included. Dance showed a significant improvement over the control group in term of the Unified Parkinson’s Disease Rating Scale III (UPDRS III) after three (MD = − 4.49, 95% CI [− 6.78, − 2.21], p  = 0.00001), six, (MD = − 5.96, 95% CI [− 8.89, − 3.02], p