Acute gastric mucosal lesions caused by acute infection of non‐Helicobacter pylori Helicobacter: a case report

Background Non‐Helicobacter pylori Helicobacter (NHPH) is not widely recognized as a cause of acute gastric mucosal lesions (AGML), as only a few cases of AGML caused by NHPH have been reported. We present here one case and examine the species and eradication of NHPH together with the three previous...

Full description

Saved in:
Bibliographic Details
Published in:Helicobacter (Cambridge, Mass.) Mass.), 2021-08, Vol.26 (4), p.e12814-n/a
Main Authors: Tsukadaira, Toshihisa, Hayashi, Seiichi, Ota, Hiroyoshi, Kobayashi, Natsuko, Sekiguchi, Yasuhiro, Kodaira, Himiko, Matsumoto, Takehisa, Horiuchi, Kazuki, Negishi, Tatsuya, Kurahashi, Mari
Format: Article
Language:English
Subjects:
acute gastric mucosal lesions
Antibodies
Antigens
Biopsy
Case reports
Edema
eradication
Helicobacter
Helicobacter pylori
Infections
Lesions
Mucosa
Nausea
non‐Helicobacter pylori Helicobacter
Omeprazole
Pain
proton pump inhibitor
Vomiting
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Non‐Helicobacter pylori Helicobacter (NHPH) is not widely recognized as a cause of acute gastric mucosal lesions (AGML), as only a few cases of AGML caused by NHPH have been reported. We present here one case and examine the species and eradication of NHPH together with the three previously reported cases. Case presentation A 52‐year‐old woman presented with a two‐day history of severe epigastric pain, nausea, and vomiting. An esophagogastroduodenoscopy showed mucosal edema, multiple erosions, and ulcerations in the antrum. Biopsy specimens taken from the antrum revealed long spiral‐shaped organisms, suggesting NHPH. As both serum anti‐Helicobacter pylori (H. pylori) antibody and H. pylori stool antigen test were negative, this case was diagnosed as AGML caused by NHPH. After the administration of esomeprazole 20 mg for 14 days and the interval of the following 12 days, AGML was deemed to have been cured endoscopically. In addition, microscopic examination and PCR analysis confirmed the success of NHPH eradication. Conclusions NHPH should be considered a probable cause of AGML in cases that are not attributed to the other causes already recognized. Taking probability of spontaneous eradication into consideration, it is appropriate to start eradication therapy after confirming the chronicity of NHPH infection.
ISSN:1083-4389
1523-5378
DOI:10.1111/hel.12814