Antibacterial efficacy of copper-added chitosan nanoparticles : a confocal laser scanning microscopy analysis

[Abstract] The aim of this study was to evaluate the antibacterial efficacy of copper added chitosan nanoparticles (CU-CNPs) as an irrigation solution with different irrigants in terms of eliminating Enterococcus Faecalis (E.faecalis) from the root canals. Fifty mandibular premolar teeth were prepar...

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Bibliographic Details
Published in:Odontology 2021-10, Vol.109 (4), p.868-873
Main Authors: Keskin, N B, Aydın, Z U, Uslu, G, Özyürek, T, Erdönmez, D, Gündoğar, M
Format: Article
Language:English
Subjects:
Antibacterial activity
Cell size
Chitosan
Confocal microscopy
Copper
Dentistry
Lavage
Medicine
Nanoparticles
Oral and Maxillofacial Surgery
Original Article
Root canals
Sodium hypochlorite
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Summary:[Abstract] The aim of this study was to evaluate the antibacterial efficacy of copper added chitosan nanoparticles (CU-CNPs) as an irrigation solution with different irrigants in terms of eliminating Enterococcus Faecalis (E.faecalis) from the root canals. Fifty mandibular premolar teeth were prepared and infected with E.faecalis for 21 days. After the incubation period, samples were randomly divided into a control group irrigated with distilled water and 4 experimental groups (n=10) irrigated with as follows, %6 NaOCl, %6 NaOCl + %9 editronate (HEBP), Chitosan nanoparticles (CNPs), and CU-CNPs. To calculate the proportion of dead E.faecalis cell volume, stained using LIVE/DEAD BacLight Bacterial Viability Kit and were scanned using confocal laser scanning microscope (CLSM). All the irrigation solutions significantly (P
ISSN:1618-1247
1618-1255
DOI:10.1007/s10266-021-00613-4