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Pre-operative embolization for staged treatment of infantile choroid plexus papilloma

Choroid plexus papillomas (CPPs) are benign but rare neuroepithelial neoplasms of the choroid plexus that represent the non-malignant form of a spectrum of tumors of the choroid plexus. The vast majority of CPPs present in children under 5 years of age. Some CPPs are diagnosed prenatally, but many o...

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Bibliographic Details
Published in:Child's nervous system 2022-02, Vol.38 (2), p.429-433
Main Authors: Mangham, William M., Elijovich, Lucas, Lee-Diaz, Jorge A., Orr, Brent A., Gienapp, Andrew J., Boop, Frederick A.
Format: Article
Language:English
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Summary:Choroid plexus papillomas (CPPs) are benign but rare neuroepithelial neoplasms of the choroid plexus that represent the non-malignant form of a spectrum of tumors of the choroid plexus. The vast majority of CPPs present in children under 5 years of age. Some CPPs are diagnosed prenatally, but many of them reach a large size before diagnosis. CPPs typically present with signs and symptoms of hydrocephalus. Treatment of these tumors has traditionally been with surgical resection. Large CPPs in young children present a challenge due to risk of high blood loss during resection. Here, the authors describe the case of a 3-month-old presenting with hydrocephalus and a large CPP of the third ventricle that was managed with a staged strategy of embolization followed by a delayed resection, allowing the tumor to involute prior to surgery.
ISSN:0256-7040
1433-0350
DOI:10.1007/s00381-021-05212-w