Prostaglandin F2α regulation and function during ovulation and luteinization in cows

Although prostaglandins are important in the ovulation process, a precise role for prostaglandin F2α (PGF) has not been elucidated. This study aimed to evaluate the regulation of PGF receptor mRNA (PTGFR) in granulosa cells and the local effect of PGF on ovulation and luteinization. In Experiment 1,...

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Published in:Theriogenology 2021-09, Vol.171, p.30-37
Main Authors: Pereira de Moraes, Fabiane, Amaral D'Avila, Camila, Caetano de Oliveira, Fernando, Ávila de Castro, Natália, Diniz Vieira, Arnaldo, Schneider, Augusto, Machado Pfeifer, Luiz Francisco, Cantarelli Pegoraro, Lígia Margareth, Ferreira, Rogério, Germano Ferst, Juliana, Tomazele Rovani, Monique, Nunes Correa, Márcio, Dias Gonçalves, Paulo Bayard, Lucia, Thomaz, Garziera Gasperin, Bernardo
Format: Article
Language:English
Subjects:
Anti-inflammatory
Cattle
Ovulation
Prostaglandins
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Summary:Although prostaglandins are important in the ovulation process, a precise role for prostaglandin F2α (PGF) has not been elucidated. This study aimed to evaluate the regulation of PGF receptor mRNA (PTGFR) in granulosa cells and the local effect of PGF on ovulation and luteinization. In Experiment 1, using samples collected in vivo before (Day 2), during (Day 3) and after (Day 4) follicular deviation, expression of PTGFR in bovine granulosa cells was more abundant in the dominant follicle after deviation than in subordinates (P 
ISSN:0093-691X
1879-3231
DOI:10.1016/j.theriogenology.2021.05.008