Gender differences in clinical outcomes in myasthenia gravis: A prospective cohort study

Introduction/Aims It is uncertain whether clinical outcomes differ between male and female patients with myasthenia gravis (MG) while receiving standard clinical care. Methods In a prospective cohort study of 107 patients with MG receiving standard of care from 2012 to 2019, the Quantitative MG (QMG...

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Bibliographic Details
Published in:Muscle & nerve 2021-11, Vol.64 (5), p.538-544
Main Authors: Thomsen, Jan L. S., Vinge, Lotte, Harbo, Thomas, Andersen, Henning
Format: Article
Language:English
Subjects:
Activities of Daily Living
Female
gender
Humans
Male
myasthenia gravis
Myasthenia Gravis - drug therapy
outcome
Outcome Assessment, Health Care
prospective
Prospective Studies
Quality of Life
Sex Factors
treatment
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Summary:Introduction/Aims It is uncertain whether clinical outcomes differ between male and female patients with myasthenia gravis (MG) while receiving standard clinical care. Methods In a prospective cohort study of 107 patients with MG receiving standard of care from 2012 to 2019, the Quantitative MG (QMG), the MG Composite (MGC), the MG Activities of Daily Living (MG‐ADL), and the MG Quality of Life 15‐Items (QOL15) were determined. Clinical outcomes were analyzed in relation to gender. Results Mean follow‐up time was 4.8 (±0.4) y, and 70 patients completed all follow‐up assessments. Patients improved on all clinical scores: QMG ‐1.8 (P 
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.27331