Cerebrospinal Fluid Rhinorrhea as the First Symptom of Metastatic Prostate Adenocarcinoma

The most common cause of cerebrospinal fluid (CSF) rhinorrhoea is damage to the skull base with a dura mater’s rupture due to an accident or an iatrogenic injury. This applies to over 96% of cases. Other possibilities that can lead to CSF leakage are neoplasms of the nasal cavity, paranasal sinuses,...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2023-09, Vol.102 (9), p.NP466-NP469
Main Authors: Ostrowska, Magdalena, Wróbel, Maciej J.
Format: Article
Language:English
Subjects:
Biomarkers
Case reports
Cerebrospinal fluid
Diagnostic tests
Head & neck cancer
Metastasis
Prostate cancer
Sinuses
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Summary:The most common cause of cerebrospinal fluid (CSF) rhinorrhoea is damage to the skull base with a dura mater’s rupture due to an accident or an iatrogenic injury. This applies to over 96% of cases. Other possibilities that can lead to CSF leakage are neoplasms of the nasal cavity, paranasal sinuses, and nasopharynx. Although prostate cancer spreads to bones, cranial metastases to paranasal sinuses are extremely rare. We present a case of an 83-year-old patient with CSF leakage due to infiltrating metastatic prostate cancer. Cerebrospinal fluid rhinorrhea turned out to be the first symptom of prostate cancer metastasis. Diagnostic and treatment strategies are presented in the discussion.
ISSN:0145-5613
1942-7522
DOI:10.1177/01455613211016710