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Integrase strand transfer inhibitor treatment does not increase the incidence of immune reconstitution inflammatory syndrome in HIV‐infected Koreans

Objectives Immune reconstitution inflammatory syndrome (IRIS) is a major concern when starting antiretroviral therapy (ART) in patients with advanced HIV infection. The aim of this study was to determine the incidence and risk factors of IRIS in HIV‐infected Koreans initiating ART, and whether integ...

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Bibliographic Details
Published in:HIV medicine 2021-09, Vol.22 (8), p.705-714
Main Authors: Kim, J, Nam, H‐J, Kang, S‐J, Jung, S‐I, Hwang, CH, Kim, Y‐S, Chang, H‐H, Kim, S‐W, Park, K‐Hwa
Format: Article
Language:English
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Summary:Objectives Immune reconstitution inflammatory syndrome (IRIS) is a major concern when starting antiretroviral therapy (ART) in patients with advanced HIV infection. The aim of this study was to determine the incidence and risk factors of IRIS in HIV‐infected Koreans initiating ART, and whether integrase strand transfer inhibitor (INSTI) treatment increases the risk of IRIS. Methods This retrospective analysis included adults living with HIV, seen at four university‐affiliated hospitals in South Korea, who were naïve to ART and had a CD4 T‐cell count
ISSN:1464-2662
1468-1293
DOI:10.1111/hiv.13117