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Fabrication, evaluation and applications of dissolving microneedles

[Display omitted] In recent years, transdermal preparations have emerged as one of the most promising modes of administration. In particular, dissolving microneedles have attracted extensive attention because of their painlessness, safety, high delivery efficiency and easily operation for patients....

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Bibliographic Details
Published in:International journal of pharmaceutics 2021-07, Vol.604, p.120749-120749, Article 120749
Main Authors: Zhang, Lijing, Guo, Ranran, Wang, Siqi, Yang, Xiaotong, Ling, Guixia, Zhang, Peng
Format: Article
Language:English
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Summary:[Display omitted] In recent years, transdermal preparations have emerged as one of the most promising modes of administration. In particular, dissolving microneedles have attracted extensive attention because of their painlessness, safety, high delivery efficiency and easily operation for patients. This article mainly reviews the preparation methods, the types of matrix polymer materials, the content of dissolving microneedles performance testing, and the applications of dissolving microneedles. It is expected to lay a solid knowledge foundation for the in-depth study of the dissolving microneedles.
ISSN:0378-5173
1873-3476
DOI:10.1016/j.ijpharm.2021.120749