Molecular characterization of 23 Y chromosomal STR markers in the Gurjar population of National Capital Region (NCR), India

In the present study, DNA samples of 202 unrelated male individuals of Gurjar population were evaluated for the molecular diversity at 23 Y chromosomal Y-STR markers. Out of selected individuals, results showed 143 unique haplotypes. Highest degree of gene diversity (GD), polymorphic information con...

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Bibliographic Details
Published in:International journal of legal medicine 2022-03, Vol.136 (2), p.555-556
Main Authors: Dev, Kapil, Kesharwani, Lav, Kushwaha, Pushpesh, Kumar, Akshay, Srivastav, Kunwar Veer Vikram, Bhasney, Varsha, Kumawat, R. K., Dixit, Shivani, Srivastava, Ankit, Chaubey, Gyaneshwer, Shrivastava, Pankaj
Format: Article
Language:English
Subjects:
Deoxyribonucleic acid
Discrimination
DNA
Forensic Medicine
Forensic sciences
Haplotypes
Loci
Markers
Medical Law
Medicine
Medicine & Public Health
Population
Population Data
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Summary:In the present study, DNA samples of 202 unrelated male individuals of Gurjar population were evaluated for the molecular diversity at 23 Y chromosomal Y-STR markers. Out of selected individuals, results showed 143 unique haplotypes. Highest degree of gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was observed as 0.7941, 0.7590, and 0.7902, respectively, for the locus DYS385a/b. Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. The haplotype data of the present study will not only enrich the existing Indian Y-STR data but will also be useful for forensic DNA application.
ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-021-02623-x