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Molecular characterization of 23 Y chromosomal STR markers in the Gurjar population of National Capital Region (NCR), India
In the present study, DNA samples of 202 unrelated male individuals of Gurjar population were evaluated for the molecular diversity at 23 Y chromosomal Y-STR markers. Out of selected individuals, results showed 143 unique haplotypes. Highest degree of gene diversity (GD), polymorphic information con...
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Published in: | International journal of legal medicine 2022-03, Vol.136 (2), p.555-556 |
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creator | Dev, Kapil Kesharwani, Lav Kushwaha, Pushpesh Kumar, Akshay Srivastav, Kunwar Veer Vikram Bhasney, Varsha Kumawat, R. K. Dixit, Shivani Srivastava, Ankit Chaubey, Gyaneshwer Shrivastava, Pankaj |
description | In the present study, DNA samples of 202 unrelated male individuals of Gurjar population were evaluated for the molecular diversity at 23 Y chromosomal Y-STR markers. Out of selected individuals, results showed 143 unique haplotypes. Highest degree of gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was observed as 0.7941, 0.7590, and 0.7902, respectively, for the locus DYS385a/b. Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. The haplotype data of the present study will not only enrich the existing Indian Y-STR data but will also be useful for forensic DNA application. |
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Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. The haplotype data of the present study will not only enrich the existing Indian Y-STR data but will also be useful for forensic DNA application.</description><identifier>ISSN: 0937-9827</identifier><identifier>EISSN: 1437-1596</identifier><identifier>DOI: 10.1007/s00414-021-02623-x</identifier><identifier>PMID: 34059972</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Deoxyribonucleic acid ; Discrimination ; DNA ; Forensic Medicine ; Forensic sciences ; Haplotypes ; Loci ; Markers ; Medical Law ; Medicine ; Medicine & Public Health ; Population ; Population Data</subject><ispartof>International journal of legal medicine, 2022-03, Vol.136 (2), p.555-556</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-6693047ec8e17492377ccef5448d679104166f6425a5f363faef6771ec493fd73</cites><orcidid>0000-0002-1647-2390</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2628901736/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2628901736?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,21355,21373,27901,27902,33588,33589,33746,33747,43709,43790,73964,74053</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34059972$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dev, Kapil</creatorcontrib><creatorcontrib>Kesharwani, Lav</creatorcontrib><creatorcontrib>Kushwaha, Pushpesh</creatorcontrib><creatorcontrib>Kumar, Akshay</creatorcontrib><creatorcontrib>Srivastav, Kunwar Veer Vikram</creatorcontrib><creatorcontrib>Bhasney, Varsha</creatorcontrib><creatorcontrib>Kumawat, R. 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Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. The haplotype data of the present study will not only enrich the existing Indian Y-STR data but will also be useful for forensic DNA application.</description><subject>Deoxyribonucleic acid</subject><subject>Discrimination</subject><subject>DNA</subject><subject>Forensic Medicine</subject><subject>Forensic sciences</subject><subject>Haplotypes</subject><subject>Loci</subject><subject>Markers</subject><subject>Medical Law</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Population</subject><subject>Population Data</subject><issn>0937-9827</issn><issn>1437-1596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ALSLI</sourceid><sourceid>BGRYB</sourceid><sourceid>M0O</sourceid><recordid>eNp9UU1rFTEUDaLY59M_4EICblpwar4mmSzl0dZCrfCsC1ch5t2085yZjMkMtPrnve1rFbpwEe6F83HJOYS85uyQM2beF8YUVxUTHJ8Wsrp-QhZcSVPx2uqnZMEs7rYRZo-8KGXLGDfa1M_JnlSsttaIBfn9KXUQ5s5nGq589mGC3P7yU5sGmiIVkn5DIKc-ldT7jn65WNPe5x-QC20HOl0BPZnzFuVjGtHmQXh-t6Fg5cd2wrmGy1to_3y1PnhHT4dN61-SZ9F3BV7dzyX5enx0sfpYnX0-OV19OKuCFHqqtLaSKQOhAW6UFdKYECDWSjUbbSzHELSOWona11FqGT1EbQyHoKyMGyOXZH_nO-b0c4Yyub4tAbrOD5Dm4kQt60ZYJgRS3z6ibtOc8R_I0qKxmCBeWBKxY4WcSskQ3ZhbTOXGceZuq3G7ahxW4-6qcdcoenNvPX_vYfNX8tAFEuSOUBAaLiH_u_0f2z819Zgm</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Dev, Kapil</creator><creator>Kesharwani, Lav</creator><creator>Kushwaha, Pushpesh</creator><creator>Kumar, Akshay</creator><creator>Srivastav, Kunwar Veer Vikram</creator><creator>Bhasney, Varsha</creator><creator>Kumawat, R. 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Highest degree of gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was observed as 0.7941, 0.7590, and 0.7902, respectively, for the locus DYS385a/b. Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. 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subjects | Deoxyribonucleic acid Discrimination DNA Forensic Medicine Forensic sciences Haplotypes Loci Markers Medical Law Medicine Medicine & Public Health Population Population Data |
title | Molecular characterization of 23 Y chromosomal STR markers in the Gurjar population of National Capital Region (NCR), India |
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