Liver Blood Tests in the Management of Suspected Choledocholithiasis

Abstract Objective The likelihood of common bile duct (CBD) stones considers liver blood tests (LBTs) if they are markedly altered only. The aim of our study was to find a reliable tool based on LBTs to predict the presence of CBD stones. Methods We retrospectively considered all patients who underw...

Full description

Saved in:
Bibliographic Details
Published in:Laboratory medicine 2021-11, Vol.52 (6), p.597-602
Main Authors: Mongelli, Francesco, Di Giuseppe, Matteo, Porcellini, Iride, Proietti, Francesco, Cristaudi, Alessandra, Pini, Ramon, La Regina, Davide
Format: Article
Language:English
Subjects:
Blood
Blood tests
Cholangiopancreatography, Magnetic Resonance
Choledocholithiasis - diagnostic imaging
Gallstones
Hematologic Tests
Humans
Liver
Medical examination
Retrospective Studies
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objective The likelihood of common bile duct (CBD) stones considers liver blood tests (LBTs) if they are markedly altered only. The aim of our study was to find a reliable tool based on LBTs to predict the presence of CBD stones. Methods We retrospectively considered all patients who underwent magnetic resonance cholangiopancreatography (MRCP) because of suspected CBD stones from January 2014 to June 2019. Demographic, clinical data, and LBT values were collected and analyzed. Results We selected 191 patients, 64 (33.5%) with positive MRCP and 127 (66.5%) with negative MRCP. The analysis showed that our compound LBT-based score had 83.6%, 90.7%, and 90.6% sensitivity, specificity, and negative predictive values, respectively, in determining MRCP results. Conclusion We designed a weighted score with high diagnostic power in determining MRCP results that could help in differentiating between candidates for primary cholecystectomy and patients who benefit from preoperative MRCP.
ISSN:0007-5027
1943-7730
DOI:10.1093/labmed/lmab042