Long‐term effectiveness and safety of bladder augmentation in spina bifida patients

Aims To establish the long‐term efficacy and safety of bladder augmentation in spina bifida patients. Material and Methods Sixteen patients were operated on using the Bramble technique. Preoperative and postoperative evaluation included clinical history, blood tests, urine cultures, cystography, pye...

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Bibliographic Details
Published in:Neurourology and urodynamics 2021-08, Vol.40 (6), p.1576-1584
Main Authors: Romero‐Maroto, Jesús, Martinez‐Cayuelas, Laura, Gómez‐Pérez, Luis, Sarrió‐Sanz, Pau, Olarte Barragán, Edgar, López‐López, Ana Isabel
Format: Article
Language:English
Subjects:
Bladder
bladder dysfunction
continence
detubularized augmentation cystoplasty
Hemorrhage
Kidney transplantation
Lithiasis
Patients
Pyelonephritis
Quality of life
Sphincter
Spina bifida
Surgery
Surgical outcomes
Transplants & implants
Urinary tract infections
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Summary:Aims To establish the long‐term efficacy and safety of bladder augmentation in spina bifida patients. Material and Methods Sixteen patients were operated on using the Bramble technique. Preoperative and postoperative evaluation included clinical history, blood tests, urine cultures, cystography, pyelography, ultrasound, and filling cystometry. In the final review a standardized quality of life questionnaire was applied. Results Median follow‐up was 20 years (15–26). Kidney function was stabilized except for one case that required a kidney transplant. Hydronephrosis disappeared or improved (p = 0.03). Vesicoureteral reflux grades I–II was cured without reimplantation and grades III‐IV responded better with reimplantation than without (p = 0.03). Quality of life improved in all patients, with all stating they would undergo the procedure again. After surgery, 94% of the patients exhibited diurnal continence but 25% exhibited nocturnal incontinence. Pressure at capacity decreased and bladder capacity increased (p 
ISSN:0733-2467
1520-6777
DOI:10.1002/nau.24713