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Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York
Abstract A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variant...
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Published in: | Clinical infectious diseases 2022-03, Vol.74 (5), p.909-912 |
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container_title | Clinical infectious diseases |
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creator | Lesho, Emil Corey, Brendan Lebreton, Francois Ong, Ana C Swierczewski, Brett E Bennett, Jason W Walsh, Edward E McGann, Patrick |
description | Abstract
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021. |
doi_str_mv | 10.1093/cid/ciab507 |
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A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.</description><subject>COVID-19</subject><subject>Humans</subject><subject>Mutation</subject><subject>New York - epidemiology</subject><subject>SARS-CoV-2 - genetics</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kE1P3DAQQK2Kqny0J-7IJ7QVCtjxR5zjslpoxbaV2FKpp8ixxxDYxKmdgPYH8L9rtAtHNBrNHJ7e4SF0SMkpJSU7M41Nq2tBig9ojwpWZFKUdCf9RKiMK6Z20X6M94RQqoj4hHYZJ0qqQu2h53kL4RY6A9g7PNwBnnPFr_CPcdBD4zvcdHgJjxAAT804AL6G2DdBDz6s8XLd2eBbwDMffKcfmzBGnOPJcnq9zGb-T5Z_xYumA30L-PyUpmFcvBhv-pj0gH_CE_7rw8Nn9NHpVYQv23uAbi7mv2ffssWvy--z6SIzTBRDltfcEmJrB5qzWhjCDSlzqYR0BTeFchS4tVw6VkprpHSSlKWzArSuqQTLDtBk4-2D_zdCHKq2iQZWK92BH2OVp3iSkZLmCT3ZoCb4GAO4qg9Nq8O6oqR66V6l7tW2e6KPtuKxbsG-sa-hE3C8AfzYv2v6D3bXigk</recordid><startdate>20220309</startdate><enddate>20220309</enddate><creator>Lesho, Emil</creator><creator>Corey, Brendan</creator><creator>Lebreton, Francois</creator><creator>Ong, Ana C</creator><creator>Swierczewski, Brett E</creator><creator>Bennett, Jason W</creator><creator>Walsh, Edward E</creator><creator>McGann, Patrick</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1548-9438</orcidid></search><sort><creationdate>20220309</creationdate><title>Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York</title><author>Lesho, Emil ; Corey, Brendan ; Lebreton, Francois ; Ong, Ana C ; Swierczewski, Brett E ; Bennett, Jason W ; Walsh, Edward E ; McGann, Patrick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-2b4d00dbfea43b5c04c0926856f74c78f1e4dd46f396dc66f6099fd5eaab16ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>COVID-19</topic><topic>Humans</topic><topic>Mutation</topic><topic>New York - epidemiology</topic><topic>SARS-CoV-2 - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lesho, Emil</creatorcontrib><creatorcontrib>Corey, Brendan</creatorcontrib><creatorcontrib>Lebreton, Francois</creatorcontrib><creatorcontrib>Ong, Ana C</creatorcontrib><creatorcontrib>Swierczewski, Brett E</creatorcontrib><creatorcontrib>Bennett, Jason W</creatorcontrib><creatorcontrib>Walsh, Edward E</creatorcontrib><creatorcontrib>McGann, Patrick</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lesho, Emil</au><au>Corey, Brendan</au><au>Lebreton, Francois</au><au>Ong, Ana C</au><au>Swierczewski, Brett E</au><au>Bennett, Jason W</au><au>Walsh, Edward E</au><au>McGann, Patrick</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York</atitle><jtitle>Clinical infectious diseases</jtitle><addtitle>Clin Infect Dis</addtitle><date>2022-03-09</date><risdate>2022</risdate><volume>74</volume><issue>5</issue><spage>909</spage><epage>912</epage><pages>909-912</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><abstract>Abstract
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source | Oxford Journals Online |
subjects | COVID-19 Humans Mutation New York - epidemiology SARS-CoV-2 - genetics |
title | Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York |
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