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Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer
Background: Peri-operative variables associated with prolonged Intensive Care Unit (ICU) admission following cytoreductive surgery for ovarian cancer were investigated. Patients and Methods: A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ov...
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Published in: | Anticancer research 2021-06, Vol.41 (6), p.3059-3065 |
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container_title | Anticancer research |
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creator | COLLINS, ANNA SPOONER, STEPHANIE HORNE, JONATHAN CHAINRAI, MIRA RUNAU, FRANSCOIS BOURNE, TIM MOSS, ESTHER L. DAVIES, QUENTIN CHATTOPADHYAY, SUPRATIK BHARATHAN, RASIAH |
description | Background: Peri-operative variables associated with prolonged Intensive Care Unit (ICU) admission following cytoreductive surgery for ovarian cancer were investigated. Patients and Methods: A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ovarian cancer in a single tertiary referral centre from 2015-2019. Patients were categorized according to length of ICU stay ( |
doi_str_mv | 10.21873/anticanres.15089 |
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Patients and Methods: A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ovarian cancer in a single tertiary referral centre from 2015-2019. Patients were categorized according to length of ICU stay (<48 h and ≥48 h), and peri-operative variables were compared across the two groups. Results: A total of 56 patients were admitted to the ICU post-operatively, 37 for <48 h and 19 for ≥48 h (range=3-11 days). Greater duration of procedure and estimated blood loss, bowel resection, higher post-operative lactate level, lower post-operative albumin level and requirement for post-operative blood products were associated with prolonged ICU stay. Increased intraoperative fluid requirement was an independent predictor of extended ICU stay. Conclusion: Utilizing identified intra-operative risk factors to perform individualized risk assessments might improve planning of ICU resources. Optimizing intraoperative fluid management may improve short-term patient outcomes.</description><identifier>ISSN: 0250-7005</identifier><identifier>EISSN: 1791-7530</identifier><identifier>DOI: 10.21873/anticanres.15089</identifier><language>eng</language><publisher>Athens: International Institute of Anticancer Research</publisher><subject>Albumins ; Blood ; Cancer ; Fluid management ; Intensive care ; Lactic acid ; Ovarian cancer ; Risk analysis ; Risk assessment ; Risk factors ; Surgery</subject><ispartof>Anticancer research, 2021-06, Vol.41 (6), p.3059-3065</ispartof><rights>Copyright International Institute of Anticancer Research Jun 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-2d09056dd55ee05adbf3d9f9263a17f797892ec3d504032935a4b57623bab80d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids></links><search><creatorcontrib>COLLINS, ANNA</creatorcontrib><creatorcontrib>SPOONER, STEPHANIE</creatorcontrib><creatorcontrib>HORNE, JONATHAN</creatorcontrib><creatorcontrib>CHAINRAI, MIRA</creatorcontrib><creatorcontrib>RUNAU, FRANSCOIS</creatorcontrib><creatorcontrib>BOURNE, TIM</creatorcontrib><creatorcontrib>MOSS, ESTHER L.</creatorcontrib><creatorcontrib>DAVIES, QUENTIN</creatorcontrib><creatorcontrib>CHATTOPADHYAY, SUPRATIK</creatorcontrib><creatorcontrib>BHARATHAN, RASIAH</creatorcontrib><title>Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer</title><title>Anticancer research</title><description>Background: Peri-operative variables associated with prolonged Intensive Care Unit (ICU) admission following cytoreductive surgery for ovarian cancer were investigated. Patients and Methods: A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ovarian cancer in a single tertiary referral centre from 2015-2019. Patients were categorized according to length of ICU stay (<48 h and ≥48 h), and peri-operative variables were compared across the two groups. Results: A total of 56 patients were admitted to the ICU post-operatively, 37 for <48 h and 19 for ≥48 h (range=3-11 days). Greater duration of procedure and estimated blood loss, bowel resection, higher post-operative lactate level, lower post-operative albumin level and requirement for post-operative blood products were associated with prolonged ICU stay. Increased intraoperative fluid requirement was an independent predictor of extended ICU stay. Conclusion: Utilizing identified intra-operative risk factors to perform individualized risk assessments might improve planning of ICU resources. Optimizing intraoperative fluid management may improve short-term patient outcomes.</description><subject>Albumins</subject><subject>Blood</subject><subject>Cancer</subject><subject>Fluid management</subject><subject>Intensive care</subject><subject>Lactic acid</subject><subject>Ovarian cancer</subject><subject>Risk analysis</subject><subject>Risk assessment</subject><subject>Risk factors</subject><subject>Surgery</subject><issn>0250-7005</issn><issn>1791-7530</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpdkcFq3DAQQEVoIdttPiA3QS-9OB1bK8k6hqVJFhYSSJscjWyNtwqOtB3JW_z38W4KhZ6GgTePgcfYZQlXVVlr8c2G7DsbCNNVKaE2Z2xRalMWWgr4wBZQSSg0gDxnn1J6AVDK1GLBpgckX8Q9ks3-gPzJkrftgIlfpxQ7bzM6_uzzL_5AcYhhN6-bkDGkI722hPwx24nfxGGIf3zY8fWUI6Ebu5PvcaQd0sT7SPz-cJSH-Sp0SJ_Zx94OCS_-ziX7efP9x_qu2N7fbtbX26ITK5OLyoEBqZyTEhGkdW0vnOlNpYQtda-Nrk2FnXASViAqI6RdtVKrSrS2rcGJJfv67t1T_D1iys2rTx0Ogw0Yx9RUUmi1UrVSM_rlP_QljhTm745ULYwBo2eqfKc6iikR9s2e_KulqSmhOcVo_sVoTjHEG2regTw</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>COLLINS, ANNA</creator><creator>SPOONER, STEPHANIE</creator><creator>HORNE, JONATHAN</creator><creator>CHAINRAI, MIRA</creator><creator>RUNAU, FRANSCOIS</creator><creator>BOURNE, TIM</creator><creator>MOSS, ESTHER L.</creator><creator>DAVIES, QUENTIN</creator><creator>CHATTOPADHYAY, SUPRATIK</creator><creator>BHARATHAN, RASIAH</creator><general>International Institute of Anticancer Research</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20210601</creationdate><title>Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer</title><author>COLLINS, ANNA ; SPOONER, STEPHANIE ; HORNE, JONATHAN ; CHAINRAI, MIRA ; RUNAU, FRANSCOIS ; BOURNE, TIM ; MOSS, ESTHER L. ; DAVIES, QUENTIN ; CHATTOPADHYAY, SUPRATIK ; BHARATHAN, RASIAH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-2d09056dd55ee05adbf3d9f9263a17f797892ec3d504032935a4b57623bab80d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Albumins</topic><topic>Blood</topic><topic>Cancer</topic><topic>Fluid management</topic><topic>Intensive care</topic><topic>Lactic acid</topic><topic>Ovarian cancer</topic><topic>Risk analysis</topic><topic>Risk assessment</topic><topic>Risk factors</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>COLLINS, ANNA</creatorcontrib><creatorcontrib>SPOONER, STEPHANIE</creatorcontrib><creatorcontrib>HORNE, JONATHAN</creatorcontrib><creatorcontrib>CHAINRAI, MIRA</creatorcontrib><creatorcontrib>RUNAU, FRANSCOIS</creatorcontrib><creatorcontrib>BOURNE, TIM</creatorcontrib><creatorcontrib>MOSS, ESTHER L.</creatorcontrib><creatorcontrib>DAVIES, QUENTIN</creatorcontrib><creatorcontrib>CHATTOPADHYAY, SUPRATIK</creatorcontrib><creatorcontrib>BHARATHAN, RASIAH</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Anticancer research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>COLLINS, ANNA</au><au>SPOONER, STEPHANIE</au><au>HORNE, JONATHAN</au><au>CHAINRAI, MIRA</au><au>RUNAU, FRANSCOIS</au><au>BOURNE, TIM</au><au>MOSS, ESTHER L.</au><au>DAVIES, QUENTIN</au><au>CHATTOPADHYAY, SUPRATIK</au><au>BHARATHAN, RASIAH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer</atitle><jtitle>Anticancer research</jtitle><date>2021-06-01</date><risdate>2021</risdate><volume>41</volume><issue>6</issue><spage>3059</spage><epage>3065</epage><pages>3059-3065</pages><issn>0250-7005</issn><eissn>1791-7530</eissn><abstract>Background: Peri-operative variables associated with prolonged Intensive Care Unit (ICU) admission following cytoreductive surgery for ovarian cancer were investigated. Patients and Methods: A retrospective review was carried out of patients admitted to the ICU following cytoreductive surgery for ovarian cancer in a single tertiary referral centre from 2015-2019. Patients were categorized according to length of ICU stay (<48 h and ≥48 h), and peri-operative variables were compared across the two groups. Results: A total of 56 patients were admitted to the ICU post-operatively, 37 for <48 h and 19 for ≥48 h (range=3-11 days). Greater duration of procedure and estimated blood loss, bowel resection, higher post-operative lactate level, lower post-operative albumin level and requirement for post-operative blood products were associated with prolonged ICU stay. Increased intraoperative fluid requirement was an independent predictor of extended ICU stay. Conclusion: Utilizing identified intra-operative risk factors to perform individualized risk assessments might improve planning of ICU resources. 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subjects | Albumins Blood Cancer Fluid management Intensive care Lactic acid Ovarian cancer Risk analysis Risk assessment Risk factors Surgery |
title | Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer |
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