Red blood cell distribution width predicts residual renal function decline in patients undergoing continuous ambulatory peritoneal dialysis

• Published in: Therapeutic apheresis and dialysis 2022-02, Vol.26 (1), p.205-211
• Main Authors: Li, You Q., Bai, Jian X., Tang, Yu F., Lin, Ke X., Huang, Cheng W., Shi, Yong J.
• Format: Article
• Language: English
• Subjects: continuous ambulatory peritoneal dialysis; Erythrocyte Indices - physiology; Female; Humans; Kaplan-Meier Estimate; Kidney - physiopathology; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory - adverse effects; Peritoneal Dialysis, Continuous Ambulatory - methods; Predictive Value of Tests; red blood cell distribution width; residual renal function; Retrospective Studies; Risk Factors
• ISSN: 1744-9979; 1744-9987
• DOI: 10.1111/1744-9987.13698

To investigate the relationship between red blood cell distribution width (RDW) and residual renal function (RRF) in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Seventy‐seven CAPD patients were enrolled in this study. According to receiver operator characteristic (ROC) curve analysis, patients were divided into high RDW (RDW > 14.95%) and low RDW (RDW ≤ 14.95%) groups. The data of baseline clinical, biochemical parameters, comorbidities, medication status, peritoneal function, and dialysis adequacy were compared. Survival curves were calculated using Kaplan–Meier method. Cox regression model was employed to analyze risk factors of decline in RRF. The overall median survival time was 24 months, the median survival time of high RDW group (46 patients) and low RDW group (31 patients) were 24 and 12 months, respectively. Compared with the low RDW group, patients in the high RDW group were older, higher rate of decline RRF and white blood cells count as well as lower total Kt/V (all p