Comments on “Risk Factors for Left Ventricle Enlargement in Children With Frequent Ventricular Premature Complexes” by Bo Chen et al, June 2020

Idiopathic frequent PVCs were always considered benign in all age groups.1 However, over the past decade, frequent PVCs have emerged as a cause of left ventricular (LV) dysfunction, LV dilatation, congestive heart failure, and even sudden cardiac death in the adult population.4,5 Paediatric data on...

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Bibliographic Details
Published in:The American journal of cardiology 2021-08, Vol.152, p.178-179
Main Authors: Bertels, Robin Andrew, Harteveld, Lisette M., Blom, Nico A.
Format: Article
Language:English
Subjects:
Ablation
Abnormalities
Asymptomatic
Cardiac arrhythmia
Cardiac function
Cardiology
Catheters
Chemotherapy
Children
Congestive heart failure
Drug therapy
Enlargement
Heart failure
Medical instruments
Morphology
Patients
Pediatrics
Risk analysis
Risk factors
Tachycardia
Ventricle
Young adults
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Summary:Idiopathic frequent PVCs were always considered benign in all age groups.1 However, over the past decade, frequent PVCs have emerged as a cause of left ventricular (LV) dysfunction, LV dilatation, congestive heart failure, and even sudden cardiac death in the adult population.4,5 Paediatric data on PVCs in relation to LV dysfunction are limited. Introduction Bo Chen et al. 2020 Ventricular premature complexes (VPC), one of the most common arrhythmias, occur in patients with heart abnormalities as well as in healthy patients.1,2 In recent years, the incidence has increased significantly in children.3 Idiopathic frequent VPC were always considered benign.1 However, recent studies in adult have showed that the burden of frequent VPC might be a key factor for left ventricular (LV) dysfunction, LV dilatation and even congestive heart failure.4−9 The relation between VPC and LV dysfunction or structural changes are still unclear in children. The current guidelines of the European Society of Cardiology recommend anti-arrhythmic drug therapy or catheter ablation as a treatment option for children with symptomatic VPC /VT and rapid nonsustained VT (nsVT).10−12 Nevertheless, particularly in children, the data regarding treatment of frequent VPC /VTs to prevent LV dysfunction in asymptomatic patients is still lacking.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2021.04.028