Kaposi sarcoma of the adrenal gland: A report of two cases with a review of the literature

Kaposi sarcoma (KS) is a low-grade vascular neoplasm commonly involving mucocutaneous sites, while adrenal gland involvement is exceptional. The anaplastic variant is a rare entity characterized by marked cellular pleomorphism, increased mitosis, worse prognosis, and an increased metastatic potentia...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cancer research and therapeutics 2021-04, Vol.17 (2), p.606-608
Main Authors: Derqaoui, Sabrine, Znati, Kaoutar, Bernoussi, Zakia
Format: Article
Language:English
Subjects:
Adrenal glands
Case studies
Diagnosis
Kaposi's sarcoma
Kaposis sarcoma
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Kaposi sarcoma (KS) is a low-grade vascular neoplasm commonly involving mucocutaneous sites, while adrenal gland involvement is exceptional. The anaplastic variant is a rare entity characterized by marked cellular pleomorphism, increased mitosis, worse prognosis, and an increased metastatic potential. The diagnosis remains on histology and immunohistochemistry. We describe two cases of primary adrenal KS to report on this exceptional presentation of KS: the first case is a 67-year-old female with anaplastic KS wit fatal outcome. The second case is a 56-year-old male who presented a classic KS of the adrenal gland. Until now, no standard efficient treatment regimens have been clearly identified. There is a need for a further understanding of anaplastic KS's biology, and collecting a sizable patient cohort remains essential to review treatment outcome.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.JCRT_670_20