Interventions to prevent preterm delivery in women with short cervix before fetoscopic laser surgery for twin–twin transfusion syndrome

ABSTRACT Objective Preoperative short cervical length (CL) remains a major risk factor for preterm birth after laser surgery for twin–twin transfusion syndrome (TTTS), but the optimal intervention to prolong pregnancy remains elusive. The objective of this study was to compare secondary methods for...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2022-02, Vol.59 (2), p.169-176
Main Authors: Buskmiller, C., Bergh, E. P., Brock, C., Miller, J., Baschat, A., Galan, H., Behrendt, N., Habli, M., Peiro, J. L., Snowise, S., Fisher, J., Macpherson, C., Thom, E., Pedroza, C., Johnson, A., Blackwell, S., Papanna, R.
Format: Article
Language:English
Subjects:
cerclage
Cerclage, Cervical
Cervix
Cervix Uteri - pathology
Cervix Uteri - surgery
Combined treatment
Demographics
Demography
Female
Fetofetal Transfusion - surgery
fetoscopic laser surgery
Fetoscopy
Fetuses
Gestation
Gestational Age
Gynecology
Humans
Laser surgery
Lasers
Management
Matching
Neonates
Obstetrics
Patients
pessary
Pregnancy
Pregnancy Complications - pathology
Pregnancy Complications - surgery
Pregnancy, Twin
Premature birth
Premature Birth - prevention & control
prematurity
preterm birth
preterm delivery
Prevention
Progesterone
Risk analysis
Risk factors
Secondary analysis
short cervix
Surgery
Sutures
Transfusion
twin–twin transfusion syndrome
Ultrasonic imaging
Ultrasound
Uterine Cervical Diseases - pathology
Uterine Cervical Diseases - surgery
Vagina
Womens health
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Summary:ABSTRACT Objective Preoperative short cervical length (CL) remains a major risk factor for preterm birth after laser surgery for twin–twin transfusion syndrome (TTTS), but the optimal intervention to prolong pregnancy remains elusive. The objective of this study was to compare secondary methods for the prevention of preterm birth in twin pregnancies with TTTS undergoing fetoscopic laser photocoagulation (FLP), in the setting of a short cervix at the time of FLP, in five North American Fetal Treatment Network (NAFTNet) centers. Methods This was a secondary analysis of data collected prospectively at five NAFTNet centers, conducted from January 2013 to March 2020. Inclusion criteria were a monochorionic diamniotic twin pregnancy complicated by TTTS, undergoing FLP, with preoperative CL 
ISSN:0960-7692
1469-0705
DOI:10.1002/uog.23708