Effect of Osteoporosis on Adjacent Segmental Degeneration After Posterior Lumbar Interbody Fusion Under Whole Body Vibration

• Published in: World neurosurgery 2021-08, Vol.152, p.e700-e707
• Main Authors: Zhang, Renwen, Zhang, Chenchen, Shu, Xinnong, Yuan, Xin, Li, Yixuan, Chen, Qian, Huang, Honghao, Zeng, Qiuhong, Bu, Guojun, Li, Ruihui, Li, Shuyu, Chang, Minmin, Tang, Shujie
• Format: Article
• Language: English
• Subjects: Adjacent segmental degeneration; Finite element study; Osteoporosis; Posterior lumbar interbody fusion; Whole body vibration
• ISSN: 1878-8750; 1878-8769
• DOI: 10.1016/j.wneu.2021.06.031

Adjacent segmental degeneration (ASD) is one of the common complications after posterior lumbar interbody fusion (PLIF). Both whole body vibration (WBV) and osteoporosis are important factors associated with the biomechanics of the lumbar spine. However, to the best of our knowledge, no studies have investigated the effects of osteoporosis on ASD after PLIF under WBV. In the present study, using one normal model, one PLIF model and one PLIF with osteoporosis model of the L1–S1 segment were developed. A 5-Hz, 40-N sinusoidal vertical load was imposed on the superior surface of L1 of each model to simulate WBV, and the dynamic responses and maximal values of intradiscal pressure, shear stress on annulus fibrosus, total deformation, and disc bulge were evaluated in the L1-L2, L2-L3, L3-L4, and L5-S1 segments. At the L1-L2, L2-L3, and L3-L4 levels, the differences in the dynamic responses and maximal values in intradiscal pressure, shear stress, total deformation, and disc bulge between the PLIF and PLIF with osteoporosis models were slight. However, at the L5-S1 level, the dynamic response curves and maximal intradiscal pressure, shear stress, and disc bulge values in the PLIF with osteoporosis model were significantly lower than those in the PLIF model. Osteoporosis can mitigate the development of ASD in the lower adjacent segment but has no obvious influence on the upper adjacent segments during WBV.